Evidence map›Paper›PMID 31754887›Full record

ReviewCurrent infectious disease reports2019

Ventilator-Associated Pneumonia: Diagnostic Test Stewardship and Relevance of Culturing Practices.

Blaine Kenaa, Mary Elizabeth Richert, Kimberly C Claeys, Andrea Shipper, Kaede V Sullivan, Gregory M Schrank, Lyndsay M O'Hara, Daniel J Morgan, Carl Shanholtz, Surbhi Leekha

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current infectious disease reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. A quasi-experimental study of a bundled diagnostic stewardship intervention for ventilator-associated pneumonia.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2024
    Article
  5. Review
  6. Article
  7. Diagnostic Stewardship in the Pediatric Intensive Care Unit.Infectious disease clinics of North America · 2022
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Blaine KenaaDepartment of Medicine, Department of Pulmonary and Critical Care, University of Maryland School of Medicine, 110 S. Paca st. Second floor pulmonary, Baltimore, MD, 21201, USA. Blaine.kenaa@som.umaryland.edu.
Mary Elizabeth RichertDivision of Internal Medicine, PGY-3, Department of Medicine, University of Maryland School of Medicine, University of Maryland Medical Center, N3W42, 22 S. Greene Street, Baltimore, MD, 21201, USA.
Kimberly C ClaeysInfectious Diseases, Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, 20 N. Pine Street, Baltimore, MD, 21201, USA.
Andrea ShipperHealth Sciences and Human Services Library, University of Maryland Baltimore, 601 W. Lombard St., Baltimore, MD, 21201, USA.
Kaede V SullivanPathology and Laboratory Medicine, Medicine Education and Research Building, Lewis Katz School of Medicine, 3500 N. Broad St., Philadelphia, PA, 19140, USA.
Gregory M SchrankDivision of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, University of Maryland Medical Center, N3W42, 22 S. Greene Street, Baltimore, MD, 21201, USA.
Lyndsay M O'HaraDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, MD, 21201, USA.
Daniel J MorganDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, MD, 21201, USA.
Carl ShanholtzDepartment of Medicine, Department of Pulmonary and Critical Care, University of Maryland School of Medicine, 110 S. Paca st. Second floor pulmonary, Baltimore, MD, 21201, USA.
Surbhi LeekhaDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, MD, 21201, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewVentilator-associated pneumonia (VAP) is one of the most common infections in the ICU. Prompt diagnosis is vital as mortality increases with delayed antibiotic therapy. However, accurate diagnosis is challenging due to non-specific clinical features in a complicated patient cohort. Microbiological culture data remains a crucial aspect in confirming diagnosis. RECENT

findingsLiterature data comparing the benefit of invasive respiratory sampling to non-invasive is inconclusive. Differences in culturing practices translate in overidentification of organisms of unclear significance. Positive culture data in a low pre-test probability does not differentiate between true infection and colonization resulting in overtreatment. Furthermore, there are also opportunities for modifying the reporting of respiratory tract cultures that can better guide antimicrobial therapy. Under the umbrella of antimicrobial stewardship, diagnostic stewardship can be incorporated to create a systematic approach that would target culturing practices to match the right pre-test probability. Ideal outcome will be targeting cultures to the right patient population and minimizing unnecessary treatment.

Indexed as

Antimicrobial stewardshipDiagnostic stewardshipEndotracheal aspirateInvasive respiratory culturingSelective culture reportingVentilator-associated pneumonia

Identifiers

PMID31754887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.