Evidence map›Paper›PMID 31754876›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Increased substantia nigra echogenicity correlated with visual hallucinations in Parkinson's disease: a Chinese population-based study.

Ting Li, Jing Shi, Bin Qin, Dongsheng Fan, Na Liu, Jingnian Ni, Tianqing Zhang, Hufang Zhou, Xiaoqing Xu, Mingqing Wei and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. The relationship between obstructive sleep apnea and Parkinson's disease: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Brainstem Pathologies Correlate With Depression and Psychosis in Parkinson's Disease.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Ting LiThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Jing ShiThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Bin QinBeijing Hospital, Beijing, 100730, China.
Dongsheng FanPeking University Third Hospital, Beijing, 100191, China.
Na LiuPeking University Third Hospital, Beijing, 100191, China.
Jingnian NiThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Tianqing ZhangThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Hufang ZhouThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Xiaoqing XuThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Mingqing WeiThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Xuekai ZhangThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Xiangzhu WangThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Jianping LiuCenter for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Yongyan WangInstitute of Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Jinzhou TianThe Neurology Center, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China. jztian@hotmail.com.ORCID http://orcid.org/0000-0002-1607-5897
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNPeking University · CNBeijing Hospital · CNBeijing University of Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Beijing Municipal Science and Technology Commission Z141107002515019Capital Health Research and Development of Special SF2014-1-4191National Natural Science Foundation of China 81473518National Natural Science Foundation of China 81573824
6 · The paper itself

Abstract

As a noninvasive technique, transcranial sonography (TCS) of substantia nigra (SN) has gradually showed its effectiveness not only in diagnosis but also in understanding clinical features of Parkinson's Disease (PD). This study aimed to further evaluate TCS for clinical diagnosis of PD, and to explore the association between sonographic manifestations and visual hallucinations (VH). A total of 226 subjects including 141 PD patients and 85 controls were recruited. All participants received TCS. A series of rating scales to evaluate motor and non-motor symptoms were performed in PD patients. Results showed that 172 subjects were successfully assessed by TCS. The area of SN was greater in PD patients than that in controls (P < 0.001). As receiver-operating characteristic (ROC) curve analysis showed, the best cutoff value for the larger SN echogenicity size was 23.5 mm

Indexed as

Ultrasonography, Doppler, TranscranialAgedChinaFemaleHallucinationsHumansMaleMiddle AgedParkinson DiseaseSensitivity and SpecificitySeverity of Illness IndexSubstantia NigraVisual PerceptionClinical featuresDiagnosisParkinson’s diseaseTranscranial sonographyVisual hallucinations

Identifiers

PMID31754876
PMCPMC7039836
OpenAlexW2990518664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.