Evidence map›Paper›PMID 31754820›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020

Diagnosis of spinal lesions using perfusion parameters measured by DCE-MRI and metabolism parameters measured by PET/CT.

Jiahui Zhang, Yongye Chen, Yanyan Zhang, Enlong Zhang, Hon J Yu, Huishu Yuan, Yang Zhang, Min-Ying Su, Ning Lang

Open access · greenAbstract read
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jiahui ZhangDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Yongye ChenDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Yanyan ZhangDepartment of Nuclear Medicine, Peking University Third Hospital, Beijing, People's Republic of China.
Enlong ZhangDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Hon J YuDepartment of Radiological Sciences, Center for Functional Onco-Imaging, University of California, 164 Irvine Hall, Irvine, CA, 92697-5020, USA.
Huishu YuanDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Yang ZhangDepartment of Radiological Sciences, Center for Functional Onco-Imaging, University of California, 164 Irvine Hall, Irvine, CA, 92697-5020, USA.
Min-Ying SuDepartment of Radiological Sciences, Center for Functional Onco-Imaging, University of California, 164 Irvine Hall, Irvine, CA, 92697-5020, USA. msu@uci.edu.
Ning LangDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China. langning800129@126.com.ORCID 0000-0001-7501-1773
Peking University · CNUniversity of California, Irvine · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Prediction of Neoadjuvant Chemo Pathological Response Using MRI MarkersR01CA127927 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI SU, MIN-YING L. · 2008 to 2017
$5.0M
Mammographic Density and Metabolic Genotyping for Predicting Cancer PrognosisR21CA208938 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, JEON-HOR, SU, MIN-YING L. · 2017 to 2018
$370k
Key Clinical Projects of the Peking University Third Hospital BYSY2018007National Natural Science Foundation of China 81701648National Natural Science Foundation of China 81871326NCI NIH HHS P30 CA062203NCI NIH HHS R01 CA127927NCI NIH HHS R21 CA208938
6 · The paper itself

Abstract

purposeTo investigate the correlation of parameters measured by dynamic-contrast-enhanced MRI (DCE-MRI) and

methodsA total of 49 patients with pathologically confirmed spinal tumors, including 38 malignant, six benign and five borderline tumors, were analyzed. The MRI and PET/CT were done within 3 days, before biopsy. On MRI, the ROI was manually placed on area showing the strongest enhancement to measure pharmacokinetic parameters K

resultsThe K

conclusionsThe vascular parameters measured by DCE-MRI and glucose metabolism measured by PET/CT from the most aggressive tumor area did not show a significant correlation. The results suggest they provide complementary information reflecting different aspects of the tumor, which may aid in diagnosis of spinal lesions. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

Contrast MediaPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18HumansMagnetic Resonance ImagingPerfusionContrast MediaFluorodeoxyglucose F18Magnetic resonance imagingPositron emission tomography/computed tomographySpinal neoplasms

Identifiers

PMID31754820
PMCPMC7709817
OpenAlexW2991102840

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.