Evidence map›Paper›PMID 31754650›Full record

ArticleCommunications biology2019

A common mechanism allows selective targeting of GluN2B subunit-containing

Julian A Schreiber, Dirk Schepmann, Bastian Frehland, Simone Thum, Maia Datunashvili, Thomas Budde, Michael Hollmann, Nathalie Strutz-Seebohm, Bernhard Wünsch, Guiscard Seebohm

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Targeting NMDA Receptor Complex in Management of Epilepsy.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Characterization in nonhuman primates of (R)-[European journal of nuclear medicine and molecular imaging · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Julian A Schreiber1Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, D-48149 Münster, Germany.
Dirk Schepmann1Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, D-48149 Münster, Germany.
Bastian Frehland1Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, D-48149 Münster, Germany.
Simone Thum1Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, D-48149 Münster, Germany.
Maia Datunashvili2Institute of Physiology I, University of Münster, Robert-Koch-Str. 27a, D-48149 Münster, Germany.
Thomas Budde2Institute of Physiology I, University of Münster, Robert-Koch-Str. 27a, D-48149 Münster, Germany.
Michael Hollmann4Department of Biochemistry I - Receptor Biochemistry, Ruhr University Bochum, Universitätsstr. 150, D-44801 Bochum, Germany.
Nathalie Strutz-Seebohm5Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, D-48149 Münster, Germany.
Bernhard Wünsch *1Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, D-48149 Münster, Germany.ORCID 0000-0002-9030-8417
Guiscard Seebohm *5Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, D-48149 Münster, Germany.
University of Münster · DEUniversity Hospital Münster · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DiscoveryModels, MolecularBenzazepinesBinding SitesDose-Response Relationship, DrugHumansHydrogen BondingLigandsMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureProtein BindingReceptors, N-Methyl-D-AspartateStructure-Activity RelationshipBenzazepinesLigandsNR2B NMDA receptorReceptors, N-Methyl-D-AspartateLigand-gated ion channelsReceptor pharmacologyStructural biology

Identifiers

PMID31754650
PMCPMC6858350
OpenAlexW2984556569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.