Evidence map›Paper›PMID 31754649›Full record

ArticleCommunications biology2019

Rab5-mediated endosome formation is regulated at the

Makoto Nagano, Junko Y Toshima, Daria Elisabeth Siekhaus, Jiro Toshima

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Endocytosis and trans-Golgi Network in Yeast.Sub-cellular biochemistry · 2026
    Review
  8. Review
  9. Rethinking the Yeast Endomembrane System.Sub-cellular biochemistry · 2026
    Review
  10. Autophagy-lysosomal pathway in neurodegeneration.Molecular neurodegeneration advances · 2026
    Review
  11. Article
  12. Review
  13. Article
  14. A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  15. Role of endosomal RANKL-LGR4 signaling during osteoclast differentiation.Journal of molecular medicine (Berlin, Germany) · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Makoto Nagano1Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijyuku, Katsushika-ku, Tokyo, 125-8585 Japan.
Junko Y Toshima2School of Health Science, Tokyo University of Technology, 5-23-22 Nishikamada, Ota-ku, Tokyo, 144-8535 Japan.
Daria Elisabeth Siekhaus3Institute of Science and Technology Austria, Am Campus 1, A-3400 Klosterneuburg, Austria.ORCID 0000-0001-8323-8353
Jiro Toshima1Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijyuku, Katsushika-ku, Tokyo, 125-8585 Japan.
Tokyo University of Science · JPInstitute of Science and Technology Austria · ATTokyo University of Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early endosomes, also called sorting endosomes, are known to mature into late endosomes via the Rab5-mediated endolysosomal trafficking pathway. Thus, early endosome existence is thought to be maintained by the continual fusion of transport vesicles from the plasma membrane and the

Indexed as

Biological TransportEndocytosisEndosomesFluorescent Antibody TechniqueFungal ProteinsModels, BiologicalMutationrab5 GTP-Binding Proteinstrans-Golgi NetworkYeastsFungal Proteinsrab5 GTP-Binding ProteinsEndocytosisEndosomesGolgi

Identifiers

PMID31754649
PMCPMC6858330
OpenAlexW2984396125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.