ArticleSA journal of radiology2019
Normal measurements of the optic nerve, optic nerve sheath and optic chiasm in the adult population.
Article in SA journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Expert Panel Consensus Guidelines of the German Society of Neuroradiology on the Use of Magnetic Resonance Imaging in the Diagnosis and Monitoring of Multiple Sclerosis.Clinical neuroradiology · 2026Guideline
- Article
- Towards a Deeper Understanding of Cerebrospinal Fluid Transport in the Optic Nerve Subarachnoid Space: A Computational Approach.Annals of biomedical engineering · 2026Article
- The INI-32 dataset: An annotated computed tomography atlas of the orbit.Data in brief · 2026Article
- Automatic segmentation and volume measurement of anterior visual pathway in brain 3D-T1WI using deep learning.Frontiers in medicine · 2025Article
- Septo-optic dysplasia plus: A case report for reviewing and recognizing this conditionBiomedica : revista del Instituto Nacional de Salud · 2024Review
- Normative body mass-adjusted reference ranges of magnetic resonance imaging signs commonly used in diagnosing idiopathic intracranial hypertension in a healthy standard population.Scientific reports · 2024Article
- Atrophy of the optic chiasm is associated with microvascular diabetic complications in type 1 diabetes.Frontiers in endocrinology · 2023Article
- Normative measurements of orbital structures by magnetic resonance imaging.International ophthalmology · 2022Article
- Pediatric reference values of anterior visual pathway structures measured with axis-correction on high-resolution 3D T2 fast spin echo sequences.BMC pediatrics · 2022Article
- Article
- Implementation of deep learning-based auto-segmentation for radiotherapy planning structures: a workflow study at two cancer centers.Radiation oncology (London, England) · 2021Article
- Ultrasound Assessment of the Fetal Optic Chiasm.Journal of medical ultrasoundReview
- Correlation of optic nerve on magnetic resonance imaging with visual acuity in children with cerebral visual impairment.Oman journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImaging assessment of the anterior visual pathway structures, particularly the optic nerves (ON), requires knowledge of normal dimensions. Several studies suggesting techniques and normal ranges have been performed, but most suffer from various methodological flaws. This study is the first to be performed in a South African population.
objectivesThe aim of this study was to establish normal measurements of the ON, optic nerve sheath (ONS) and optic chiasm (OC) on magnetic resonance imaging (MRI).
methodEighty normal adults between ages of 12 and 65 years were included in this prospective, quantitative, observational, descriptive study to establish normal measurement of the ON, ONS and OC using a T2W 3D MRI sequence. Measurements (width and height) were undertaken by two observers independently.
resultsA total of 80 participants with a mean age of 35 years were studied: 49 females (61.25%) and 31 males (38.75%). There were no statistical differences in the measurements between gender and age correlation. Interobserver agreement was best for larger structures, that is, OC width and intracranial ON width, respectively. The overall mean of OC width was 13.63 mm (range: 11.13 mm-16.92 mm, standard deviation [s.d.] 1.21); intraorbital ON height at 5 mm behind the globe 2.29 mm (range: 1.63 mm-3.33 mm, s.d. 0.43), and intracranial ON width 4.27 mm (range: 2.46 mm-5.19 mm, s.d. 0.53).
conclusionNormal measurements of the anterior visual pathway structures on MRI are best reflected in the larger structures. Interobserver variability was poor for the orbital ON, ONS, intracranial ON height and OC height. We recommend that measurements be obtained for the OC width and intracranial ON width. The overall mean for the OC width is 13.63 mm and intracranial ON width 4.27 mm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.