ReviewEFORT open reviews2019
Implant materials and prosthetic joint infection: the battle with the biofilm.
Review in EFORT open reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05239312 (Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital), which is not on this map. Cited by 72 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital
Who cites it
72 citing papers in PubMed, 128 citations in OpenAlex.
- Effective therapy for periprosthetic joint infection through sequential application of non-contact low-frequency ultrasonic debridement and antiseptic solutions.Bone & joint research · 2026Article
- Biofilm Formation Patterns ofAntibiotics (Basel, Switzerland) · 2026Article
- Nanostructured Hydrogels: A Method to Prevent Biofilms on Implantable Medical Devices.Gels (Basel, Switzerland) · 2026Review
- Article
- High intra- and inter-observer reliability of the PJI-TNM classification in acute and chronic periprosthetic hip joint infection.Journal of bone and joint infection · 2026Article
- Article
- Test parameter selection affects the perceived antibacterial efficacy of a contact-killing coating developed to prevent prosthetic joint infection.Frontiers in bioengineering and biotechnology · 2026Article
- The Influence of Antibiotic-Loaded Bone Cement Spacer Type on Outcomes of the First Stage of a Revision Total Hip Arthroplasty.Antibiotics (Basel, Switzerland) · 2025Article
- Characterizing interactions of Staphylococcus aureus and Escherichia coli in dual-species implant-associated biofilms.NPJ biofilms and microbiomes · 2025Article
- Biofilm Formation, c-di-GMP Production, and Antimicrobial Resistance in Staphylococcal Strains Isolated from Prosthetic Joint Infections: A Pilot Study in Total Hip and Knee Arthroplasty Patients.International journal of molecular sciences · 2025Article
- Antimicrobial resistance in orthopedics: microbial insights, clinical impact, and the necessity of a multidisciplinary approach-a review.Acta orthopaedica · 2025Review
- Single-Stage Revision for Treatment of Prosthetic Joint Infection in Total Hip Arthroplasty.Indian journal of orthopaedics · 2025Review
- A Novel Seven-Day Abbreviated Two-Stage Exchange Arthroplasty with Intra-Articular Antibiotic Irrigation for Chronic Periprosthetic Joint Infection of the Knee: A Case Report.Journal of orthopaedic case reports · 2025Article
- EngineeredBioactive materials · 2025Article
- Local Antimicrobial Potential of Bupivacaine and Tolfenamic Acid-Loaded Ultra-High Molecular Weight Polyethylene (UHMWPE) for Orthopedic Infection.Bioengineering (Basel, Switzerland) · 2025Article
- Calcium hydroxide coating for orthopedic implants: evaluation of osseointegrative and antibacterial propertiesFrontiers in bioengineering and biotechnology · 2025Article
- Evaluation of bacterial adherence and biofilm development on an anodized stainless-steel surface for the prevention of osteosynthesis-associated infections.Journal of bone and joint infection · 2025Article
- A rapid-release pure iodine coating on titanium implants to mitigate acute periprosthetic infections.Frontiers in bioengineering and biotechnology · 2025Article
- Establishing hospital-specific background microbial libraries to reduce false positives in mNGS diagnosis of periprosthetic joint infection.Frontiers in cellular and infection microbiology · 2025Article
- Influence of zirconium dioxide (ZrOFrontiers in bioengineering and biotechnology · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prosthetic joint infection (PJI) is associated with poor clinical outcomes and is expensive to treat.Although uncommon overall (affecting between 0.5% and 2.2% of cases), PJI is one of the most commonly encountered complications of joint replacement and its incidence is increasing, putting a significant burden on healthcare systems.Once established, PJI is extremely difficult to eradicate as bacteria exist in biofilms which protect them from antibiotics and the host immune response.Improved understanding of the microbial pathology in PJI has generated potential new treatment strategies for prevention and eradication of biofilm associated infection including modification of implant surfaces to prevent adhesion of bacteria.Much research is currently ongoing looking at different implant surface coatings and modifications, and although most of this work has not translated into clinical medicine there has been some early clinical success. Cite this article:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.