ReviewEFORT open reviews2019
Developmental dysplasia of the hip: a systematic literature review of the genes related with its occurrence.
Review in EFORT open reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Developmental Dysplasia of the Hip in Saudi Arabia and the Gulf Countries:Saudi medical journal · 2026Pooled it
- Clinical efficacy of robot-assisted total hip arthroplasty for developmental dysplasia of the hip: A meta-analysis.Joint diseases and related surgery · 2026Pooled it
- 'THA for DDH: replacement principles and techniques - femoral side'.EFORT open reviews · 2026Review
- Article
- Tenotomy of gluteus medium and gluteus minimus is associated with dysplasia of the hip: an experimental study in rabbits.European journal of medical research · 2025Article
- Genome-Wide mRNA and lncRNA Expression Profiling to Uncover Their Role in the Molecular Pathogenesis of Developmental Dysplasia of the Hip.International journal of molecular sciences · 2025Article
- Association of hip dysplasia in newborns with ethnicity using graf method ultrasound.Pakistan journal of medical sciences · 2025Article
- Physical Therapy Management for Delayed Diagnosis of Developmental Dysplasia of the Hip: A Case Report.Case reports in pediatrics · 2025Article
- Environmental and Genetic Risk Factors in Developmental Dysplasia of the Hip for Early Detection of the Affected Population.Diagnostics (Basel, Switzerland) · 2024Article
- Microstructure changes and miRNA-mRNA network in a developmental dysplasia of the hip rat model.iScience · 2024Article
- Molecular mechanisms and genetic factors contributing to the developmental dysplasia of the hip.Frontiers in genetics · 2024Review
- Early detection and risk factors of congenital hip dislocation in Morocco.Journal of public health in Africa · 2023Article
- Residual acetabular dysplasia after Pavlik harness treatment for Graf type II hips.Journal of children's orthopaedics · 2023Article
- Whole exome sequencing of 28 families of Danish descent reveals novel candidate genes and pathways in developmental dysplasia of the hip.Molecular genetics and genomics : MGG · 2023Article
- Anatomical characteristics and potential gene mutation sites of a familial recurrent patellar dislocation.BMC medical genomics · 2022Article
- Comprehensive bioinformatics analysis of susceptibility genes for developmental dysplasia of the hip.Intractable & rare diseases research · 2022Article
- Clinical and Genetic Features of Chinese Adult Patients With Chronic Non-Bacterial Osteomyelitis: A Single Center Report.Frontiers in immunology · 2022Article
- Integrative Analysis of MicroRNA and mRNA Sequencing Data Identifies Novel Candidate Genes and Pathways for Developmental Dysplasia of Hip.Cartilage · 2021Article
- MiR-4303 relieves chondrocyte inflammation by targeting ASPN in osteoarthritis.Journal of orthopaedic surgery and research · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developmental dysplasia of the hip (DDH) is one of the most prevalent congenital malformations. It has a wide spectrum of anatomical abnormalities of the hip joint and is characterized by mild or incomplete formation of the acetabulum leading to laxity of the joint capsule, secondary deformity of the proximal femur and irreducible hip dislocation. It is the leading cause of early hip osteoarthritis in young individuals.Both genetic and environmental factors have been proposed to play an important role in the pathogenesis of DDH. A high prevalence is present in Asian, Caucasian, Mediterranean and American populations, with females being more frequently affected. We evaluated a variety of genetic studies indexed in the PubMed database.Several susceptive genes, including WISP3, PAPPA2, HOXB9, HOXD9, GDF5, TGF Beta 1, CX3CR1, UQCC, COL1A1, TbX4 and ASPN have been identified as being associated with the development of DDH. Moreover, genetic association has also been reported between hip dysplasia and other comorbidities. Even though genetic components are a crucial part in the aetiology of DDH, several DDH susceptibility genes need further investigation.The purpose of this review is to present current literature evidence regarding genes responsible for DDH development. Cite this article:
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.