Evidence map›Paper›PMID 31754041›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Cardiovascular risks impact human brain

Joshua Chiappelli, Laura M Rowland, S Andrea Wijtenburg, Hongji Chen, Andrew A Maudsley, Sulaiman Sheriff, Shuo Chen, Anya Savransky, Wyatt Marshall, Meghann C Ryan and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Microbiome · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Joshua ChiappelliMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228; jchiappe@som.umaryland.edu lrowland@som.umaryland.edu.ORCID 0000-0001-6121-7439
Laura M RowlandMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228; jchiappe@som.umaryland.edu lrowland@som.umaryland.edu.
S Andrea WijtenburgMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Hongji ChenMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Andrew A MaudsleyDepartment of Radiology, University of Miami School of Medicine, Miami, FL 33136.
Sulaiman SheriffDepartment of Radiology, University of Miami School of Medicine, Miami, FL 33136.
Shuo ChenMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Anya SavranskyMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Wyatt MarshallMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Meghann C RyanMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Heather A BruceMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
Alan R ShuldinerDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201.
Braxton D MitchellDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201.
Peter KochunovMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
L Elliot HongMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228.
University of Maryland, Baltimore · USUniversity of Miami · US

Funding

The Effects of Kynurenine Aminotransferase Inhibition in People with SchizophreniaP50MH103222 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT · 2014 to 2023
$25.2M
SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
Amish Connectome Project on Mental IllnessU01MH108148 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2015 to 2018
$4.3M
Towards Multisystem-Brain Successful Aging in Schizophrenia SpectrumR01MH116948 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HONG, L ELLIOT ELLIOT · 2018 to 2022
$3.7M
A Multivariate Mediation and Deep Learning Framework for Genome-Connectome -Substance Use ResearchDP1DA048968 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI CHEN, SHUO · 2019 to 2023
$2.3M
Development and Maintenance of Software for MR Spectroscopic ImagingR01EB016064 · NIBIB · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MAUDSLEY, ANDREW A. · 2013 to 2021
$2.0M
Multimodal neuroimaging study of relational learning in schizophreniaR01MH094520 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI ROWLAND, LAURA M · 2012 to 2016
$1.9M
The Role of Stress-Immune-Connectome Disruption in Mechanisms of Chinese Early Schizophrenia SpectrumR01MH112180 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT · 2017 to 2021
$1.0M
Biomarkers and Mechanisms of Stress Pathophysiology in Early SchizophreniaK23MH112010 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI CHIAPPELLI, JOSHUA · 2017 to 2020
$763k
Hybrid GPU/CPU Computing Resource to Support Connectomic and GenomicsS10OD023696 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI KOCHUNOV, PETER V. · 2018 to 2018
$593k
NIBIB NIH HHS R01 EB015611NIBIB NIH HHS R01 EB016064NIDA NIH HHS DP1 DA048968NIH HHS S10 OD023696NIMH NIH HHS K23 MH112010NIMH NIH HHS P50 MH103222NIMH NIH HHS R01 MH094520NIMH NIH HHS R01 MH112180NIMH NIH HHS R01 MH116948NIMH NIH HHS U01 MH108148
6 · The paper itself

Abstract

Cardiovascular risk factors such as dyslipidemia and hypertension increase the risk for white matter pathology and cognitive decline. We hypothesize that white matter levels of

Indexed as

AdultAspartic AcidBlood PressureCardiovascular DiseasesEcho-Planar ImagingFemaleGray MatterHumansMaleMiddle AgedRisk FactorsWhite MatterYoung AdultAspartic AcidN-acetylaspartatecreatinehypertensionneurochemistrywhite matter

Identifiers

PMID31754041
PMCPMC6911181
OpenAlexW2990890613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.