Evidence map›Paper›PMID 31753921›Full record

ReviewThe Journal of biological chemistry2020

Changing of the guard: How the Lyme disease spirochete subverts the host immune response.

George Chaconas, Mildred Castellanos, Theodore B Verhey

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Hitchhiker's Guide toJournal of bacteriology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Evolution of theMicrobiology spectrum · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George ChaconasDepartment of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta T2N 4N1, Canada; Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada. Electronic address: chaconas@ucalgary.ca.
Mildred CastellanosDepartment of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta T2N 4N1, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
Theodore B VerheyDepartment of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta T2N 4N1, Canada; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
University of Calgary · CA

Funding

CIHR PJT-153336
6 · The paper itself

Abstract

Lyme disease, also known as Lyme borreliosis, is the most common tick-transmitted disease in the Northern Hemisphere. The disease is caused by the bacterial spirochete

Indexed as

Antigenic VariationAnimalsAntigens, BacterialBacterial ProteinsBorrelia burgdorferiGenetic LociHost-Pathogen InteractionsHumansImmunityLipoproteinsLyme DiseaseModels, MolecularMutationAntigens, BacterialBacterial ProteinsLipoproteinsVlsE protein, Borrelia burgdorferiantigenic variationbacterial geneticsbacterial pathogenesisBorreliaDNA mismatch repairDNA recombinationgene conversiongenetic polymorphismG-quadruplexinfectious diseaseLyme disease

Identifiers

PMID31753921
PMCPMC6956529
OpenAlexW2990828448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.