Evidence map›Paper›PMID 31753824›Full record

ArticleBMJ case reports2019

Possible pitfalls in the workup of ectopic ACTH secretion illustrated by four rare cases.

Jorianne Boers, P Christine Oldenburg-Ligtenberg, Aline Me Stades, Mark Jc van Treijen

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jorianne BoersDepartment of Internal Medicine, Meander Medical Centre, Amersfoort, Utrecht, The Netherlands.
P Christine Oldenburg-LigtenbergDepartment of Internal Medicine, Meander Medical Centre, Amersfoort, Utrecht, The Netherlands.
Aline Me StadesDepartment of Endocrinology, University Medical Center Utrecht, Utrecht, The Netherlands.
Mark Jc van TreijenDepartment of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands M.J.C.vanTreijen@umcutrecht.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this case report, we highlight four different cases of ectopic adrenocorticotropic hormone (ACTH) secretion with different pitfalls in the diagnostic workup. Ectopic ACTH secretion (EAS) is an uncommon cause of Cushing's syndrome that accompanies a variety of tumours. It is associated with significant morbidity and mortality. This underlines the importance of early and adequate diagnosis. We will review the causes of EAS and their presentation to increase awareness of this rare and progressive disease.

Indexed as

ACTH Syndrome, EctopicAgedCushing SyndromeDiagnosis, DifferentialFemaleHumansMaleMiddle AgedTreatment Outcomeendocrinologymetabolic disorders

Identifiers

PMID31753824
PMCPMC6887400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.