Trial reportDrug and alcohol dependence2020
Methadone treatment of arrestees: A randomized clinical trial.
Trial report in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Diversity inclusion in United States opioid pharmacological treatment trials: A systematic review.Experimental and clinical psychopharmacology · 2021Pooled it
- Assessing the impact of jail-initiated medication for opioid use disorder: A multisite analysis of the SOMATICS collaborative.PloS one · 2024Trial
- Extended-release naltrexone for youth with opioid use disorder.Journal of substance abuse treatment · 2021Trial
- Randomized trial of methadone treatment of arrestees: 24-month post-release outcomes.Drug and alcohol dependence · 2021Trial
- A randomized comparison of extended-release naltrexone with or without patient navigation vs enhanced treatment-as-usual for incarcerated adults with opioid use disorder.Journal of substance abuse treatment · 2020Trial
- Impact of methadone treatment initiated in jail on subsequent arrest.Journal of substance abuse treatment · 2020Trial
- A self-assessment of opioid use disorder services at a Pacific Northwest County jail.Substance abuse treatment, prevention, and policy · 2025Article
- National consensus statement on opioid agonist treatment in custodial settings.The Medical journal of Australia · 2025Article
- The role of recovery peer navigators in retention in outpatient buprenorphine treatment: a retrospective cohort study.Annals of medicine · 2024Article
- Community-based substance use treatment programs for reentering justice-involved adults: A scoping review.Drug and alcohol dependence reports · 2024Article
- An Ancillary Effect of Patient Navigation Following Detox: Fewer Arrests.Journal of benefit-cost analysis · 2024Article
- Medications for opioid use disorder during incarceration and post-release outcomes.Health & justice · 2023Article
- Scoping review of interventions to link individuals to substance use services at discharge from jail.Journal of substance abuse treatment · 2022Article
- Opioid-specific medication-assisted therapy and its impact on criminal justice and overdose outcomes.Campbell systematic reviews · 2022Article
- Legal System Involvement and Opioid-Related Overdose Mortality in U.S. Department of Veterans Affairs Patients.American journal of preventive medicine · 2022Article
- Interim methadone - Effective but underutilized: A scoping review.Drug and alcohol dependence · 2021Article
- Views of barriers and facilitators to continuing methadone treatment upon release from jail among people receiving patient navigation services.Journal of substance abuse treatment · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundOpioid use disorder is common among detainees in US jails, yet methadone treatment is rarely initiated.
methodsThis is a three-group randomized controlled trial in which 225 detainees in Baltimore treated for opioid withdrawal were assigned to: (1) interim methadone (IM) with patient navigation (IM + PN); (2) IM; or (3) enhanced treatment-as-usual (ETAU). Participants in both IM groups were able to enter standard methadone treatment upon release, while ETAU participants received an assessment/referral number. Follow-up assessments at 1, 3, 6, and 12 months post-release determined treatment enrollment, urine drug testing results, self-reported days of drug use, criminal activity, and overdose events. Generalized linear mixed modelling examined two planned contrasts: (1) IM groups combined vs. ETAU; and (2) IM + PN vs. IM.
resultsOn an intention-to-treat basis, compared to ETAU, significantly more participants in the combined IM groups were in treatment 30 days post-release, while the IM + PN vs. IM groups did not significantly differ. By month 12, there were no significant differences in the estimated marginal means of enrollment in any kind of drug treatment (0.40 and 0.27 for IM + PN and IM groups, respectively, compared to 0.29 for ETAU). There were no significant differences for either contrast in opioid-positive tests, although all groups reported a sharp decrease in heroin use from baseline to follow-up. There were five fatal overdoses, but none occurred during methadone treatment.
conclusionInitiating methadone treatment in jail was effective in promoting entry into community-based drug abuse treatment but subsequent treatment discontinuation attenuated any potential impact of such treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.