ArticleHeart & lung : the journal of critical care
Cross-classification of physical and affective symptom clusters and 180-day event-free survival in moderate to advanced heart failure.
Article in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Patient-centred understanding of quality of life, symptoms, health equity in cystic fibrosis (PULSE-CF): study protocol for an observational study.BMJ open respiratory research · 2026Article
- Characteristics and predictors of persistent somatic symptoms in patients with cardiac disease.Scientific reports · 2024Article
- Which of these symptom trajectories is not like the other?European journal of cardiovascular nursing · 2024Article
- Sympathetic dysfunction is associated with worse fatigue and early and subtle symptoms in heart failure: an exploratory sex-stratified analysis.European journal of cardiovascular nursing · 2024Article
- Background and Design of the Biological and Physiological Mechanisms of Symptom Clusters in Heart Failure (BIOMES-HF) Study.Journal of cardiac failure · 2022Article
- Article
- Exploring the Evolution of Heart Failure Symptoms After Hospitalization and Associations With Social Determinants of Health and Demographic Characteristics.The Journal of cardiovascular nursingObservational
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundThe relationship between physical and affective symptom clusters in heart failure (HF) is unclear.
objectivesTo identify associations between physical and affective symptom clusters in HF and to quantify outcomes and determinants of symptom subgroups.
methodsThis was a secondary analysis of data from two cohort studies among adults with HF. Physical and affective symptom clusters were compared using cross-classification modeling. Cox proportional hazards modeling and multinomial logistic regression were used to identify outcomes and determinants of symptom subgroups, respectively.
resultsIn this young, mostly male sample (n = 274), physical and affective symptom clusters were cross-classified in a model with acceptable fit. Three symptom subgroups were identified: congruent-mild (69.3%), incongruent (13.9%), and congruent-severe (16.8%). Compared to the congruent-mild symptom group, the incongruent symptom group had significantly worse 180-day event-free survival.
conclusionCongruence between physical and affective symptom clusters should be considered when identifying patients at higher risk for poor outcomes.
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