Evidence map›Paper›PMID 31753124›Full record

ArticleThe Journal of investigative dermatology2019

A Niche for Plasma Cells: The Skin.

Selda Karaaslan, Mary M Tomayko

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. A skinAnnals of translational medicine · 2021
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Selda KaraaslanDepartment of Dermatology, Yale University, New Haven, Connecticut, USA.
Mary M TomaykoDepartment of Dermatology, Yale University, New Haven, Connecticut, USA; Department of Pathology, Yale University, New Haven, Connecticut, USA. Electronic address: mary.tomayko@yale.edu.
Yale University · US

Funding

B Cell Memory Regulation by Bone Morphogenetic Protein Receptor 1AR01AI122448 · NIAID · YALE UNIVERSITY · PI TOMAYKO, MARY · 2015 to 2019
$2.2M
Elucidating functional properties of memory B cellsK08AI078533 · NIAID · YALE UNIVERSITY · PI TOMAYKO, MARY · 2008 to 2012
$774k
NIAID NIH HHS K08 AI078533NIAID NIH HHS R01 AI122448
6 · The paper itself

Abstract

Antibodies are key components of the skin immune barrier, and antibodies directed toward skin structures can result in disease. Wilson et al. (2019) show that healthy skin is a niche for antibody secreting plasma cells and plasmablasts, and that inflammation and immunization increase their numbers. This work advances our understanding of skin associated B and plasma cells in health and disease.

Indexed as

ImmunizationPlasma CellsHumansImmunoglobulin MInflammationSkinImmunoglobulin M

Identifiers

PMID31753124
PMCPMC12262100
OpenAlexW2985541678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.