ArticleThe British journal of psychiatry : the journal of mental science2020
Incidence of ischaemic heart disease and stroke among people with psychiatric disorders: retrospective cohort study.
Article in The British journal of psychiatry : the journal of mental science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Polygenic risk of major depressive disorder as a risk factor for venous thromboembolism.Blood advances · 2023Pooled it
- Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis.PLoS medicine · 2022Pooled it
- Mental disorders, receipt of cardiac care following myocardial infarction and the impact of the COVID-19 pandemic: a cohort study.BMJ open · 2026Article
- Mental disorders, mortality following myocardial infarction, and the impact of the COVID-19 pandemic in England: a cohort study.European heart journal. Quality of care & clinical outcomes · 2026Article
- Exploring the Causality Between Mood Swings and Neurological Diseases: A Mendelian Randomization Study.Brain and behavior · 2026Article
- Baseline household income is associated with severity and course of severe mental illness.Psychological medicine · 2026Article
- Health care workers' experiences of exercise in forensic psychiatry: a qualitative focus group study.International journal of qualitative studies on health and well-being · 2025Article
- Article
- Cardiovascular comorbidities in Chinese inpatients with schizophrenia spectrum disorders.Schizophrenia (Heidelberg, Germany) · 2025Article
- Depression and physical multimorbidity: A cohort study of physical health condition accrual in UK Biobank.PLoS medicine · 2025Article
- Do patients with bipolar disorders have an increased risk of stroke? A systematic review and meta-analysis.Pakistan journal of medical sciences · 2024Article
- Secondary Stroke Prevention in People With Schizophrenia.Journal of the American Heart Association · 2024Article
- Severe mental illness and cardioprotective medication prescribing: a qualitative study in general practice.BJGP open · 2024Article
- Stroke and suicide among people with severe mental illnesses.Scientific reports · 2024Article
- Sex-Related Differences in the Prevalence of Classical, Non-Classical Risk Factors and Management of the Chronic Coronary Syndrome.Journal of clinical medicine · 2023Article
- A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment.Current atherosclerosis reports · 2022Review
- The Association of Persistent Symptoms of Depression and Anxiety with Recurrent Acute Coronary Syndrome Events: A Prospective Observational Study.Healthcare (Basel, Switzerland) · 2022Article
- Galectin-1 alleviates myocardial ischemia-reperfusion injury by reducing the inflammation and apoptosis of cardiomyocytes.Experimental and therapeutic medicine · 2022Article
- Cardiovascular disease in patients with severe mental illness.Nature reviews. Cardiology · 2021Review
- Cardiovascular risk in patients with severe mental illness in Italy.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPsychiatric disorders are associated with increased risk of ischaemic heart disease (IHD) and stroke, but it is not known whether the associations or the role of sociodemographic factors have changed over time.
aimsTo investigate the association between psychiatric disorders and IHD and stroke, by time period and sociodemographic factors.
methodWe used Scottish population-based records from 1991 to 2015 to create retrospective cohorts with a hospital record for psychiatric disorders of interest (schizophrenia, bipolar disorder or depression) or no record of hospital admission for mental illness. We estimated incidence and relative risks of IHD and stroke in people with versus without psychiatric disorders by calendar year, age, gender and area-based deprivation level.
resultsIn all cohorts, incidence of IHD (645 393 events) and stroke (276 073 events) decreased over time, but relative risks decreased for depression only. In 2015, at the mean age at event onset, relative risks were 2- to 2.5-fold higher in people with versus without a psychiatric disorder. Age at incidence of outcome differed by cohort, gender and socioeconomic status. Relative but not absolute risks were generally higher in women than men. Increasing deprivation conveys a greater absolute risk of IHD for people with bipolar disorder or depression.
conclusionsDespite declines in absolute rates of IHD and stroke, relative risks remain high in those with versus without psychiatric disorders. Cardiovascular disease monitoring and prevention approaches may need to be tailored by psychiatric disorder and cardiovascular outcome, and be targeted, for example, by age and deprivation level.
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