Evidence map›Paper›PMID 31752563›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Synthesis and biological evaluation of novel thienopyrimidine derivatives as diacylglycerol acyltransferase 1 (DGAT-1) inhibitors.

Dong Jin Hong, Seung Hyun Jung, Jisook Kim, Danbee Jung, Young Gil Ahn, Kwee Hyun Suh, Kyung Hoon Min

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Discovery of thieno[3,2-RSC advances · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dong Jin HongCollege of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Seung Hyun JungHanmi Research Center, Hanmi Pharm. Co., Ltd., Gyeonggi-Do, Republic of Korea.
Jisook KimHanmi Research Center, Hanmi Pharm. Co., Ltd., Gyeonggi-Do, Republic of Korea.
Danbee JungCollege of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Young Gil AhnHanmi Research Center, Hanmi Pharm. Co., Ltd., Gyeonggi-Do, Republic of Korea.
Kwee Hyun SuhHanmi Research Center, Hanmi Pharm. Co., Ltd., Gyeonggi-Do, Republic of Korea.
Kyung Hoon MinCollege of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Hanmi Pharmaceutical (South Korea) · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel series of thieno[3,2-

Indexed as

AnimalsDiacylglycerol O-AcyltransferaseDogsDose-Response Relationship, DrugEnzyme InhibitorsHumansMaleMiceMice, Inbred ICRMolecular StructurePyrimidinesStructure-Activity RelationshipDGAT1 protein, humanDiacylglycerol O-AcyltransferaseEnzyme InhibitorsPyrimidinesthienopyrimidineDGAT-1obesitysmall moleculesthienopyrimidinetype 2 diabetes

Identifiers

PMID31752563
PMCPMC6882492
OpenAlexW2990317354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.