ArticleGenes2019
Genome-Wide Association Study of Body Mass Index and Body Fat in Mexican-Mestizo Children.
Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Novel Insights Into the Causal Effects and Shared Genetics Between Body Fat and Parkinson Disease.CNS neuroscience & therapeutics · 2024Pooled it
- Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Genotypic and phenotypic consequences of domestication in dogs.G3 (Bethesda, Md.) · 2026Article
- Alzheimer's disease multi-ancestry genome-wide interaction and stratified study with smoking.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Genotypic and phenotypic consequences of domestication in dogs.bioRxiv : the preprint server for biology · 2025Article
- Genome-wide identification of selection signatures across altitudinal gradients in dairy sheep breeds.Scientific reports · 2025Article
- Deletion of the Clock GeneThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Determinants of obesity in Latin America.Nature metabolism · 2024 · on this mapReview
- Genetics and Epigenetics in Obesity: What Do We Know so Far?Current obesity reports · 2023Review
- Genetic improvement of economic traits in Murrah buffalo using significant SNPs from genome-wide association study.Tropical animal health and production · 2023Article
- Article
- Genome-wide association analysis of milk production, somatic cell score, and body conformation traits in Holstein cows.Frontiers in veterinary science · 2022Article
- Genome-Wide Association Analysis of Growth Curve Parameters in Chinese Simmental Beef Cattle.Animals : an open access journal from MDPI · 2021Article
- An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations.Frontiers in genetics · 2021Review
- Genetics of early growth traits.Human molecular genetics · 2020Review
- Genetic Epidemiology in Latin America: Identifying Strong Genetic Proxies for Complex Disease Risk Factors.Genes · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildhood obesity is a major health problem in Mexico. Obesity prevalence estimated by body mass index (BMI) is almost half than that estimated by percent body fat (%BF) in the Childhood Obesity pediatric cohort (COIPIS).
objectiveWe performed a genome-wide association study (GWAS) of BMI and %BF in 828 children from the COIPIS to identify markers of predisposition to high values for both phenotypes used for obesity classification.
methodsFor the GWAS we used the LAT Axiom 1, Affymetrix and 2.5 million single loci from the 1000 Genomes Phase 3 imputation panel. We used a linear model, adjusted by age, sex, and Amerindian ancestry assuming an additive inheritance model.
resultsGenome-wide significance (p ≤ 5.0 × 10 DISCUSSION: None of the SNPs were previously reported as being associated to BMI or %BF. In addition, different loci were found for BMI and %BF. These results highlight the importance of gaining deeper understanding of genetic markers of predisposition to high values for the phenotypes used for obesity diagnosis.
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Registered trials
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