Evidence map›Paper›PMID 31752417›Full record

ArticlePolymers2019

Transferrin-Conjugated Docetaxel-PLGA Nanoparticles for Tumor Targeting: Influence on MCF-7 Cell Cycle.

Sajan Jose, Cinu Thomas A, Rosmy Sebastian, Shoja M H, Aleykutty N A, Alessandra Durazzo, Massimo Lucarini, Antonello Santini, Eliana B Souto

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 87 citations in OpenAlex.

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  20. A Review of Nanotechnology for Treating Dysfunctional Placenta.Frontiers in bioengineering and biotechnology · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Sajan JoseDepartment of Pharmaceutical Sciences, Mahatma Gandhi University, Cheruvandoor Campus, Ettumanoor 686631, India.
Cinu Thomas ADepartment of Pharmaceutical Sciences, Mahatma Gandhi University, Cheruvandoor Campus, Ettumanoor 686631, India.
Rosmy SebastianDepartment of Pharmaceutical Sciences, Mahatma Gandhi University, Cheruvandoor Campus, Ettumanoor 686631, India.
Shoja M HCollege of Pharmaceutical Sciences, Manipal University, Manipal 576104, India.
Aleykutty N ACaritas College of Pharmacy, Kottayam 686630, India.
Alessandra DurazzoCREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Massimo LucariniCREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Antonello SantiniDepartment of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy.
Eliana B SoutoCEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Mahatma Gandhi University · INCaritas Hospital · INManipal Academy of Higher Education · INUniversity of Coimbra · PTUniversity of Naples Federico II · IT

Funding

: Nutraceutica come supporto nutrizionale nel paziente oncologico, CUP: B83D18000140007All India Council for Technical Education (AICTE), New Delhi, India, Research Promotion Scheme (RPS 2012-2013)Portuguese Foundation for Science and Technology (FCT/MEC) the project M-ERA-NET-0004/2015 (PAIRED), through national funds, and co-financed by FEDER, under the Partnership Agreement PT2020
6 · The paper itself

Abstract

Targeted drug delivery systems are commonly used to improve the therapeutic index of anti-cancer drugs by increasing their selectivity and reducing systemic distribution and toxicity. Ligand-conjugated nanoparticles (NPs) can be effectively applied for active chemotherapeutic targeting to overexpressed receptors of tumor cells. In this study, transferrin (T

Indexed as

docetaxel trihydratefactorial designPLGA nanoparticlestransferrin conjugatetumor targeting

Identifiers

PMID31752417
PMCPMC6918445
OpenAlexW2990297243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.