Evidence map›Paper›PMID 31752312›Full record

ReviewGenes2019

Evolving Role of RING1 and YY1 Binding Protein in the Regulation of Germ-Cell-Specific Transcription.

Izabella Bajusz, Surya Henry, Enikő Sutus, Gergő Kovács, Melinda K Pirity

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. TheGenes · 2020
    Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Izabella BajuszBiological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary.
Surya HenryBiological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary.
Enikő SutusBiological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary.
Gergő KovácsBiological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary.
Melinda K PirityBiological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary.
HUN-REN Szegedi Biológiai Kutatóközpont · HUUniversity of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Separation of germline cells from somatic lineages is one of the earliest decisions of embryogenesis. Genes expressed in germline cells include apoptotic and meiotic factors, which are not transcribed in the soma normally, but a number of testis-specific genes are active in numerous cancer types. During germ cell development, germ-cell-specific genes can be regulated by specific transcription factors, retinoic acid signaling and multimeric protein complexes. Non-canonical polycomb repressive complexes, like ncPRC1.6, play a critical role in the regulation of the activity of germ-cell-specific genes. RING1 and YY1 binding protein (RYBP) is one of the core members of the ncPRC1.6. Surprisingly, the role of Rybp in germ cell differentiation has not been defined yet. This review is focusing on the possible role of Rybp in this process. By analyzing whole-genome transcriptome alterations of the

Indexed as

Gene Expression Regulation, DevelopmentalModels, GeneticTranscription, GeneticAnimalsBinding SitesCarcinogenesisCell DifferentiationCell LineCell LineageEmbryonic Stem CellsGene Expression Regulation, NeoplasticGene Knockout TechniquesGene Regulatory NetworksHumansNeoplasms, Germ Cell and EmbryonalPolycomb Repressive Complex 1Polycomb Repressive Complex 1Receptors, Retinoic AcidRepressor Proteinsapoptosisgerm cell differentiationmeiosisNanogncPRC1Oct4polycomb repressionretinoic acidRybpSall4transcriptional regulationtranscriptomeubiquitylation

Identifiers

PMID31752312
PMCPMC6895862
OpenAlexW2986856627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.