Evidence map›Paper›PMID 31752279›Full record

ReviewMolecules (Basel, Switzerland)2019

A Survey of Molecular Imaging of Opioid Receptors.

Paul Cumming, János Marton, Tuomas O Lilius, Dag Erlend Olberg, Axel Rominger

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Synthesis and In Silico Profile Modeling of 6-International journal of molecular sciences · 2025
    Article
  4. Review
  5. Investigation of [Scientific reports · 2024
    Article
  6. Brain PET imaging usingJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  7. Optimization of a Nucleophilic Two-Step Radiosynthesis of 6-International journal of molecular sciences · 2023
    Article
  8. 6-O-(2-[Molecular imaging and biology · 2023
    Article
  9. Strategies for the Production of [Organic process research & development · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Copper-Mediated Radiocyanation of Unprotected Amino Acids and Peptides.Journal of the American Chemical Society · 2022
    Article
  15. Article
  16. Evaluation of Specific Binding of [ACS medicinal chemistry letters · 2021
    Article
  17. Seasonal Variation in the Brain μ-Opioid Receptor Availability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 5 countries.

Paul CummingDepartment of Nuclear Medicine, University of Bern, Inselspital, Freiburgstraße 18, 3010 Bern, Switzerland.ORCID 0000-0002-0257-9621
János MartonABX Advanced Biochemical Compounds, Biomedizinische Forschungsreagenzien GmbH, Heinrich-Glaeser-Strasse 10-14, D-1454 Radeberg, Germany.
Tuomas O LiliusCenter for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark.ORCID 0000-0002-8361-3683
Dag Erlend OlbergSchool of Pharmacy, University of Oslo, Norwegian Medical Cyclotron Centre, N-0372 Oslo, Norway and Norwegian Medical Cyclotron Centre Ltd., Sognsvannsveien 20, N-0372 Oslo, Norway.ORCID 0000-0001-7630-675X
Axel RomingerDepartment of Nuclear Medicine, University of Bern, Inselspital, Freiburgstraße 18, 3010 Bern, Switzerland.
University of Bern · CHABX-CRO Advanced Pharmaceutical Services (Germany) · DEUniversity of Copenhagen · DKUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of endogenous peptide ligands for morphine binding sites occurred in parallel with the identification of three subclasses of opioid receptor (OR), traditionally designated as μ, δ, and κ, along with the more recently defined opioid-receptor-like (ORL1) receptor. Early efforts in opioid receptor radiochemistry focused on the structure of the prototype agonist ligand, morphine, although

Indexed as

Molecular ImagingAnimalsBiomarkersBrainBrain DiseasesHumansLigandsMental DisordersNeuroimagingPeptidesPositron-Emission TomographyRadioactive TracersReceptors, OpioidBiomarkersLigandsPeptidesRadioactive TracersReceptors, Opioiddrug dependenceepilepsymovement disordersopioid receptorspainpositron emission tomographyradiotracersμOR-, δOR-, κOR- and ORL1-ligands

Identifiers

PMID31752279
PMCPMC6891617
OpenAlexW2985834917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.