Evidence map›Paper›PMID 31751440›Full record

ArticleArquivos brasileiros de cardiologia2019

Impact of Transcatheter Aortic Valve Implantation on Kidney Function.

Rita Calça, Rui C Teles, Patrícia Branco, Augusta Gaspar, João Brito, Tiago Nolasco, Manuel D Almeida, José P Neves, Miguel Mendes, Domingos S Machado and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Rita CalçaNephrology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.ORCID 0000-0001-8960-2363
Rui C TelesCardiology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.ORCID 0000-0002-7952-6878
Patrícia BrancoNephrology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
Augusta GasparNephrology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
João BritoCardiology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
Tiago NolascoCardiotoracic Surgery department Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
Manuel D AlmeidaCardiology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
José P NevesCardiotoracic Surgery department Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
Miguel MendesCardiology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
Domingos S MachadoNephrology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
André WeigertNephrology department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisboa - Portugal.
Centro Hospitalar de Lisboa Ocidental · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is frequently present in patients with aortic valve disease. Decreased kidney perfusion as a consequence of reduced cardiac output may contribute to renal dysfunction in this setting.

objectiveGiven the potential reversibility of kidney hypoperfusion after valve repair, this study aimed to analyze the impact of percutaneous transcatheter aortic valve implantation (TAVI) on kidney function.

methodsWe performed a retrospective analysis of 233 consecutive patients who underwent TAVI in a single center between November 2008 and May 2016. We assessed three groups according to their baseline estimated glomerular filtration rate (eGFR) (mL/min/1.73 m2): Group 1 with eGFR ≥ 60; Group 2 with 30 ≤ eGFR < 60; and Group 3 with eGFR < 30. We analyzed the eGFR one month and one year after TAVI in these three groups, using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula to calculate it.

resultsPatients from Group 1 had a progressive decline in eGFR one year after the TAVI procedure (p < 0.001 vs. pre-TAVI). In Group 2 patients, the mean eGFR increased one month after TAVI and continued to grow after one year (p = 0.001 vs. pre-TAVI). The same occurred in Group 3, with the mean eGFR increasing from 24.4 ± 5.1 mL/min/1.73 m2 before TAVI to 38.4 ± 18.8 mL/min/1.73 m2 one year after TAVI (p = 0.012).

conclusionsFor patients with moderate-to-severe CKD, kidney function improved one year after the TAVI procedure. This outcome is probably due to better kidney perfusion post-procedure. We believe that when evaluating patients that might need TAVI, this 'reversibility of CKD effect' should be considered.

Indexed as

AgedAged, 80 and overAortic Valve StenosisComorbidityFemaleGlomerular Filtration RateHumansMaleMiddle AgedRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsTranscatheter Aortic Valve Replacement

Identifiers

PMID31751440
PMCPMC7021263
OpenAlexW2981116677

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.