ArticleIEEE transactions on bio-medical engineering2020
Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty.
Article in IEEE transactions on bio-medical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Fast robot-to-iOCT calibration using conical geometry and 2D cross-scan OCT.Journal of biomedical optics · 2026Article
- Corneal Endothelium Regeneration with Decellularized Porcine Corneal Extracellular Matrix Scaffolds.Tissue engineering and regenerative medicine · 2025Article
- Robotics and optical coherence tomography: current works and future perspectives [Invited].Biomedical optics express · 2025Review
- Design and Evaluation of an Eye Mountable AutoDALK Robot for Deep Anterior Lamellar Keratoplasty.Micromachines · 2024Article
- Autonomous Needle Navigation in Subretinal Injections via iOCT.IEEE robotics and automation letters · 2024Article
- Visualization of Cataract Surgery Steps With 4D Microscope-Integrated Swept-Source Optical Coherence Tomography in Ex Vivo Porcine Eyes.Translational vision science & technology · 2024Article
- Using the language of surgery to enhance ophthalmology surgical education.Surgery open science · 2023Review
- Comparison of Robot-Assisted and Manual Cannula Insertion in Simulated Big-Bubble Deep Anterior Lamellar Keratoplasty.Micromachines · 2023Article
- OCT-guided Robotic Subretinal Needle Injections: A Deep Learning-Based Registration Approach.Proceedings. IEEE International Conference on Bioinformatics and Biomedicine · 2022Article
- Ex Vivo Evaluation of a Pressure-Sensitive Device to Aid Big Bubble Intrastromal Dissection in Deep Anterior Lamellar Keratoplasty.Translational vision science & technology · 2022Article
- Optical coherence tomography refraction and optical path length correction for image-guided corneal surgery.Biomedical optics express · 2022Article
- Data-Driven Modelling and Control for Robot Needle Insertion in Deep Anterior Lamellar Keratoplasty.IEEE robotics and automation letters · 2022Article
- Investigation of Micro-motion Kinematics of Continuum Robots for Volumetric OCT and OCT-guided Visual Servoing.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2021Article
- Noise reduction by adaptive-SIN filtering for retinal OCT images.Scientific reports · 2021Article
- CNN-based CP-OCT sensor integrated with a subretinal injector for retinal boundary tracking and injection guidance.Journal of biomedical optics · 2021Article
- Physician-Friendly Tool Center Point Calibration Method for Robot-Assisted Puncture Surgery.Sensors (Basel, Switzerland) · 2021Article
- A Novel Wax Based Piezo Actuator for Autonomous Deep Anterior Lamellar Keratoplasty (Piezo-DALK).Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and SystemsArticle
- Downward viewing common-path optical coherence tomography guided hydro-dissection needle for DALK.Proceedings of SPIE--the International Society for Optical EngineeringArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveDeep anterior lamellar keratoplasty (DALK) significantly reduces the post-transplantation morbidity in patients eligible for partial-thickness cornea grafts. The popular "big bubble" technique for DALK is so challenging, however, that a significant fraction of corneal pneumodissection attempts fail for surgeons without extensive DALK-specific experience, even with previous-generation cross-sectional optical coherence tomography (OCT) guidance. We seek to develop robotic, volumetric OCT-guided technology capable of facilitating or automating the difficult needle insertion step in DALK.
methodsOur system provides for real-time volumetric corneal imaging, segmentation, and tracking of the needle insertion to display feedback for surgeons and to generate needle insertion plans for robotic execution. We include a non-automatic mode for cooperative needle control for stabilization and tremor attenuation, and an automatic mode in which needle insertion plans are generated based on OCT tracking results and executed under surgeon hold-to-run control by the robot arm. We evaluated and compared freehand, volumetric OCT-guided, cooperative, and automatic needle insertion approaches in terms of perforation rate and final needle depth in an ex vivo human cornea model.
resultsVolumetric OCT visualization reduces cornea perforations and beneficially increases final needle depth in manual insertions by clinically significant amounts. Our automatic robotic needle insertion techniques meet or exceed surgeon performance in both needle placement and perforation rate.
conclusionVolumetric OCT is a key enabler for surgeons, although robotic techniques can reliably replicate their performance. SIGNIFICANCE: Robotic needle control and volumetric OCT promise to improve outcomes in DALK.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.