Evidence map›Paper›PMID 31750895›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2020

Impact of Combined Lifestyle Factors on All-Cause and Cause-Specific Mortality and Life Expectancy in Chinese: The Singapore Chinese Health Study.

Xiong-Fei Pan, Yanping Li, Oscar H Franco, Jian-Min Yuan, An Pan, Woon-Puay Koh

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Modeling the Impact of Behavior Changes on Mortality Attributable to Non-communicable Diseases in Canada.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Xiong-Fei PanDepartment of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yanping LiDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Oscar H FrancoInstitute of Social and Preventive Medicine (ISPM), University of Bern, Switzerland.
Jian-Min YuanUPMC Hillman Cancer Center, University of Pittsburgh, Pennsylvania.
An PanDepartment of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Woon-Puay KohHealth Services and Systems Research, Duke-NUS Medical School Singapore, Singapore.

Funding

Prospective studies of cancer etiology and prevention in Shanghai and SingaporeR01CA144034 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2010 to 2014
$7.0M
THE SINGAPORE COHORT STUDY OF DIET AND CANCERR01CA080205 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YUAN, JIAN-MIN · 1999 to 2009
$5.3M
Cancer epidemiology cohorts in Shanghai and Singapore UM1CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2014 to 2018
$4.3M
NCI NIH HHS R01 CA080205NCI NIH HHS R01 CA144034NCI NIH HHS UM1 CA182876
6 · The paper itself

Abstract

backgroundTo examine the impact of combined lifestyle factors on premature mortality and life expectancy in Chinese adults.

methodsA total of 44,052 Chinese adults aged 45-74 years free of cardiovascular disease (CVD), cancer, and diabetes were followed from recruitment (1993-1998) to the end of 2016 in the Singapore Chinese Health Study. A composite score (0-5 scale) was calculated based on five baseline healthy lifestyle factors including healthy diet, nonsmoking status, light to moderate alcohol drinking, being physically active and optimal body mass index. Mortality cases were identified through linkage with the nationwide death registry.

resultsAdopting five healthy versus none was associated with a lower risk of all-cause and cause-specific mortality, and the hazard ratio (95% confidence interval [CI]) was 0.38 (0.29, 0.51) for all-cause mortality, 0.26 (0.13, 0.52) for CVD mortality, and 0.59 (0.37, 0.92) for cancer mortality. Nonadherence to 4-5 healthy lifestyle factors accounted for 34.9% (95% CI = 29.2, 40.2) in population attributable fraction for all-cause mortality, 35.1% (23.7, 44.9) for CVD mortality, and 18.0% (6.5, 28.0) for cancer mortality. Conversely, adherence to 4-5 healthy lifestyle factors versus none could achieve a gain of 8.1 years in women and 6.6 years in men for the life expectancy at 50 years.

conclusionsA healthier lifestyle is associated with a substantially reduced risk of mortality and a longer life expectancy in the Chinese population. Our findings highlight the necessity of coordinated actions targeting combined lifestyle factors in reducing the overall burden of diseases and premature deaths.

Indexed as

Cause of DeathLife ExpectancyLife StyleMortality, PrematureAgedFemaleHumansMaleMiddle AgedSingaporeCancerCardiovascular diseaseLife expectancyLifestyleMortality

Identifiers

PMID31750895
PMCPMC7566531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.