Evidence map›Paper›PMID 31750608›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Photocontrolled Dopamine Polymerization on DNA Origami with Nanometer Resolution.

Pia Winterwerber, Sean Harvey, David Y W Ng, Tanja Weil

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
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  10. Synergistically remodulating HChemical science · 2023
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Functional DNA-Polymer Conjugates.Chemical reviews · 2021
    Review
  18. Review
  19. Rationally Programming Nanomaterials with DNA for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pia WinterwerberMax Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Sean HarveyMax Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
David Y W NgMax Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Tanja WeilMax Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0002-5906-7205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temporal and spatial control over polydopamine formation on the nanoscale can be achieved by installing an irradiation-sensitive polymerization system on DNA origami. Precisely distributed G-quadruplex structures on the DNA template serve as anchors for embedding the photosensitizer protoporphyrin IX, which-upon irradiation with visible light-induces the multistep oxidation of dopamine to polydopamine, producing polymeric structures on designated areas within the origami framework. The photochemical polymerization process allows exclusive control over polydopamine layer formation through the simple on/off switching of the light source. The obtained polymer-DNA hybrid material shows significantly enhanced stability, paving the way for biomedical and chemical applications that are typically not possible owing to the sensitivity of DNA.

Indexed as

Photochemical ProcessesPolymerizationDNADopamineG-QuadruplexesNanostructuresDNADopamineDNA nanotubesDNA origamiphotopolymerizationpolydopaminestability in water

Identifiers

PMID31750608
PMCPMC7186833

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.