Evidence map›Paper›PMID 31750329›Full record

ArticleWorld journal of clinical cases2019

Normal values of shear wave velocity in liver tissue of healthy children measured using the latest acoustic radiation force impulse technology.

Pei-Xuan Sun, Yu-Yang Tong, Jing Shi, Huan Zhang, Shi-Jian Liu, Jun Du

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Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Pei-Xuan SunDiagnostic Imaging Center, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Yu-Yang TongDepartment of Ultrasound, Shanghai Cancer Center, Fudan University, Shanghai 200032, China.
Jing ShiDiagnostic Imaging Center, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Huan ZhangDiagnostic Imaging Center, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Shi-Jian LiuDepartment of Clinical Epidemiology and Biostatistics, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
Jun DuDiagnostic Imaging Center, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China. scmcdujun@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have demonstrated the feasibility and effectiveness of using ultrasound elastography to assess liver tissue stiffness. Virtual touch imaging quantification (VTIQ) based on acoustic radiation force impulse imaging has been developed as a latest and noninvasive method for assessing liver stiffness in children.

aimTo determine the standard value in healthy children, and to identify possible factors that might influence the VTIQ measurement.

methodsWith the ethical approval, 202 children between 1 month and 15 years old were included in this study. None of them had any liver or systematic diseases. All children had a normal ultrasound scan and normal body mass index (BMI) range. The subjects were divided into four age and BMI groups. The effects of gender, age, liver lobe, measurement depth, and BMI on liver elasticity were investigated.

resultsA significant correlation was found between age and shear wave velocity (SWV) value. At measurement depths of 1.5 cm and 2.0 cm in the left lobe, there were significant differences among the age groups. SWV values were significantly negatively correlated with the measurement depth. Gender, liver lobe, and BMI showed no significant effect on the SWV values. Age and BMI may influence the quality of the elastogram.

conclusionVTIQ is a noninvasive technique that is feasible to measure liver stiffness in children. The afore-mentioned velocity value obtained utilizing VTIQ method could be used as reference value for normal liver stiffness in children.

Indexed as

Acoustic radiation force impulseLiver stiffnessShear wave velocityVirtual touch imaging quantification

Identifiers

PMID31750329
PMCPMC6854399

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