Evidence map›Paper›PMID 31749885›Full record

ArticleArchives of medical science : AMS2019

Mechanism of microRNA-431-5p-

Xiaoyong Han, Xirui Wang, Hui Li, Hui Zhang

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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  6. Brain Acetyl-CoA Production and Phosphorylation of Cytoskeletal Proteins Are Targets of CYP46A1 Activity Modulation and Altered Sterol Flux.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xiaoyong HanThird Department of Neurosurgery, CangZhou Central Hospital, CangZhou, Hebei, China.
Xirui WangThird Department of Neurosurgery, CangZhou Central Hospital, CangZhou, Hebei, China.
Hui LiDepartment of Surgery, Dongguang County Chinese Traditional Medicine Hospital, CangZhou, Hebei, China.
Hui ZhangThird Department of Neurosurgery, CangZhou Central Hospital, CangZhou, Hebei, China.
Cangzhou Central Hospital · CNJining Traditional Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlioblastoma multiforme (GBM) is a kind of malignant brain tumor prevalent in adults, with the characteristics well adapted to poorly immunogenic and hypoxic conditions. Effective treatment of GBM is impeded due to the high proliferation, migration and invasion of GBM cells. GBM cells migrate by degrading the extracellular matrix, so it is difficult to have GBM cells eradicated completely by surgery. This study aims to confirm that miR-431-5p could influence the proliferation, invasion and migration of human glioblastoma multiforme cells by targeting MATERIAL AND

methodsThe expression levels of miR-431-5p and

resultsMiR-431-5p was overexpressed in GBM tissues while

conclusionsMiR-431-5p facilitated the progression of GBM by inhibiting

Indexed as

EPB41L1glioblastoma multiformemiR-431-5pU87

Identifiers

PMID31749885
PMCPMC6855151
OpenAlexW2979640794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.