Evidence map›Paper›PMID 31749871›Full record

ArticleArchives of medical science : AMS2019

Clinicopathological factors associated with novel prognostic markers for patients with triple negative breast cancer.

Anna M Badowska-Kozakiewicz, Michał P Budzik, Anna Liszcz, Maciej T Sobieraj, Aleksandra I Czerw, Maria Sobol, Janusz Patera, Andrzej Deptała

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anna M Badowska-KozakiewiczDepartment of Biophysics and Human Physiology, Medical University of Warsaw, Warsaw, Poland.
Michał P BudzikDepartment of Biophysics and Human Physiology, Medical University of Warsaw, Warsaw, Poland.
Anna LiszczStudents' Scientific Organization at the Medical University of Warsaw, Warsaw, Poland.
Maciej T SobierajStudents' Scientific Organization at the Medical University of Warsaw, Warsaw, Poland.
Aleksandra I CzerwDepartment of Health Economics and Medical Law, Medical University of Warsaw, Warsaw, Poland.
Maria SobolDepartment of Biophysics and Human Physiology, Medical University of Warsaw, Warsaw, Poland.
Janusz PateraDepartment of Pathomorphology, Military Institute of Health Services, Warsaw, Poland.
Andrzej DeptałaDepartment of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PLNational Institute of Public Health · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTriple negative breast cancer (TNBC) is characterized by a worse prognosis than other breast cancer subtypes. TNBC is defined by lack of expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2. The aim of this analysis was to evaluate the relationship between immunohistochemical expression of novel prognostic markers (erythropoietin (EPO) and erythropoietin receptor (EPO-R)) and clinicopathological features of TNBC and non-TNBC patients. MATERIAL AND

methodsOur analysis was conducted on a group of 162 patients with breast carcinoma with lymph node metastasis (111 TNBC and 51 non-TNBC). All statistical analyses were performed with SPSS software v 12.0.

resultsHistopathologic subtyping of the 111 triple negative breast cancers identified 89.1% invasive ductal carcinomas of no special type and 10.9% other special types of cancers. TNBC more often presented EPO-R and EPO expression (36%; 37.8%) than non-TNBC (23.5%; 29.4%). Non-TNBC subgroup showed statistically significant correlation only between Ki-67 expression and histological grade (G1-G3) (

conclusionsThe relationship between the expression of EPO-R and histological malignancy grade in triple negative breast cancer, suggests that the present EPO-R expression in TNBC may constitute an additional prognostic factor.

Indexed as

erythropoietinerythropoietin receptorimmunohistochemical examinationtriple negative breast cancer

Identifiers

PMID31749871
PMCPMC6855147
OpenAlexW2905214364

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.