ArticleArchives of medical science : AMS2019
Increased carotid plaque burden in patients with family medical history of premature cardiovascular events in the absence of classical risk factors.
Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- An open B-mode ultrasound database for deep learning-based atherosclerotic plaque segmentation.Scientific data · 2026Article
- Effect of information motivation behavioral skills model based dietary patterns on carotid atherosclerosis in elderly hypertensive patients.Scientific reports · 2025Article
- Adherence to Dietary Patterns and Cardiovascular Disease Risk: A Cross-Sectional Study of Total Carotid Plaque Area in Argentina.Journal of lipid and atherosclerosis · 2024Article
- The underlying mechanisms of FGF2 in carotid atherosclerotic plaque development revealed by bioinformatics analysis.Archives of medical science : AMS · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe hypothesis that relates atherosclerosis to traditional risk factors (TRF) seems to be not as adequate as previously thought; other risk factors (RF) need to be considered to prevent atherosclerosis progression. Although a family medical history of premature cardiovascular events (FHx) has been considered the putative RF for decades, it has not been incorporated routinely into cardiovascular risk evaluation along with another RF. The objective of this study was to investigate whether FHx is associated with a higher atherosclerotic burden, measured as carotid total plaque area (TPA) in a population having no traditional RF. MATERIAL AND
methodsThe study included 4,351 primary care patients in Argentina. After excluding a personal history of cardiovascular disease (CVD) and TRF: hypertension, diabetes mellitus, hypercholesterolemia, smoking history, and body mass index (BMI) > 25 kg/cm
resultsCompared with 44 matched controls, TPA was 77% higher in FHx patients (
conclusionsThe FHx was associated with increased TPA burden and progression in the absence of other TRF. This supports ultrasound screening in FHx patients in order to detect high-risk patients who may benefit from early intervention.
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