Evidence map›Paper›PMID 31749864›Full record

ArticleArchives of medical science : AMS2019

Association of lipoprotein(a) and major adverse cardiovascular events in patients with percutaneous coronary intervention.

Zhihao Chen, Chaohui Jiang, Huimin Qu, Shuang Liang, Jian Yang, Hui Wu, Chao He, Xinan Wang

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. PCSK-9 Inhibitors Can Significantly Improve the Coronary Slow Flow Caused by Elevated Lipoprotein (a) in ST-Elevation Myocardial Infarction Patients With Chronic Kidney Disease.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  4. Article
  5. Lipoprotein(a) is Associated with Sarcopenia in Patients with Type 2 Diabetes: A cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhihao ChenDepartment of Cardiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Chaohui JiangDepartment of Cardiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Huimin QuDepartment of Cardiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Shuang LiangDepartment of Cardiology, Xiang'an Hospital of Xiamen University, Xiamen, China.
Jian YangDepartment of Cardiology, The First College of Clinical Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Hui WuDepartment of Cardiology, The First College of Clinical Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Chao HeDepartment of Cardiology, The First College of Clinical Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Xinan WangDepartment of Cardiology, The First College of Clinical Medical Sciences, China Three Gorges University, Yichang, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the current study was to evaluate the association between lipoprotein(a) [Lp(a)] and major adverse cardiovascular events (MACEs) in patients with percutaneous coronary intervention (PCI) treatment. MATERIAL AND

methodsThis was a retrospective study. The demographics, prior medical histories, comorbidities and laboratory parameters were collected from the electronic health record. All participants were followed up for 1 year after the indexed PCI. Studied end points were a composite of MACEs including all-cause mortality, non-fatal myocardial infarction (MI), non-fatal ischemic stroke, transient ischemic attack and stent restenosis.

resultsDuring 1-year follow-up, 87 MACEs occurred. Compared to patients who did not have MACEs, patients who had MACEs were older, more likely to have higher body mass index, diabetes mellitus and left main lesion, and also had higher baseline low density lipoprotein cholesterol (LDL-C) and Lp(a) levels. All patients in both groups were prescribed aspirin and clopidogrel at discharge. Nearly 97.4% and 95.4% of patients in both groups were treated with statins and a higher proportion of patients in the MACE group were treated with ezetimibe (11.5% vs. 3.5%,

conclusionsBaseline serum Lp(a) can be used to predict MACEs in patients after PCI treatment, which was independent of LDL-C.

Indexed as

lipoprotein(a)major adverse cardiovascular eventspercutaneous coronary intervention

Identifiers

PMID31749864
PMCPMC6855154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.