Evidence map›Paper›PMID 31749863›Full record

ReviewArchives of medical science : AMS2019

Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis.

Željko Reiner, Luis E Simental-Mendía, Massimiliano Ruscica, Niki Katsiki, Maciej Banach, Khalid Al Rasadi, Tannaz Jamialahmadi, Amirhossein Sahebkar

Abstract readReview
In one paragraph

Review in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023
    Review
  7. Vascular Aging: Assessment and Intervention.Clinical interventions in aging · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. State of the Art Review: Brachial-Ankle PWV.Journal of atherosclerosis and thrombosis · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Željko ReinerUniversity Hospital Center Zagreb, Department of Internal Medicine, School of Medicine, University of Zagreb, Zagreb, Croatia.
Luis E Simental-MendíaBiomedical Research Unit, Mexican Social Security Institute, Durango, Mexico.
Massimiliano RuscicaDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy.
Niki KatsikiSecond Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippocration Hospital, Thessaloniki, Greece.
Maciej BanachDepartment of Hypertension, WAM University Hospital in Lodz, Medical University of Lodz, Lodz, Poland.
Khalid Al RasadiDepartment of Clinical Biochemistry, Sultan Qaboos University Hospital, Muscat, Oman.
Tannaz JamialahmadiHalal Research Center of IRI, FDA, Tehran, Iran.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this meta-analysis was to establish whether vascular pulse wave velocity (PWV) as a measure of arterial stiffness is changed in patients with familial hypercholesterolemia (FH). MATERIAL AND

methodsStudies comparing PWV between patients with FH and controls were searched in PubMed-Medline, SCOPUS, Web of Science and Google Scholar databases (up to November 26, 2017). A meta-analysis was conducted using Comprehensive Meta-Analysis V2 software. A random-effects model (using the DerSimonian-Laird method) and the generic inverse variance method were used to compensate for the heterogeneity of studies concerning demographic characteristics and differences in the studies' design.

resultsThis meta-analysis of 8 studies involving 317 patients with FH and 244 non-FH individuals did not suggest a significantly altered PWV in FH patients versus controls (weighted mean difference (WMD): 0.17 m/s, 95% confidence interval (CI): -0.31, 0.65,

conclusionsThis meta-analysis suggests that FH patients do not have significantly altered PWV when compared with normocholesterolemic individuals. However, a subanalysis of studies in which IMT was measured indicated that IMT is increased in FH patients compared with controls.

Indexed as

arterial stiffnessfamilial hypercholesterolemiaintima-media thicknesspulse wave velocity

Identifiers

PMID31749863
PMCPMC6855171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.