Evidence map›Paper›PMID 31749828›Full record

ArticleFrontiers in genetics2019

A Pediatric Case of Glioblastoma Multiforme Associated With a Novel Germline p.His112CysfsTer9 Mutation in the

Aleksandra Stajkovska, Sanja Mehandziska, Rodney Rosalia, Margarita Stavrevska, Marija Janevska, Martina Markovska, Ivan Kungulovski, Zan Mitrev, Goran Kungulovski

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Aleksandra StajkovskaSector of Genetics, Bio Engineering LLC, Skopje, Macedonia.
Sanja MehandziskaLaboratory of Genetics and Personalized Medicine, Zan Mitrev Clinic, Skopje, Macedonia.
Rodney RosaliaLaboratory of Genetics and Personalized Medicine, Zan Mitrev Clinic, Skopje, Macedonia.
Margarita StavrevskaLaboratory of Genetics and Personalized Medicine, Zan Mitrev Clinic, Skopje, Macedonia.
Marija JanevskaSector of Genetics, Bio Engineering LLC, Skopje, Macedonia.
Martina MarkovskaSector of Genetics, Bio Engineering LLC, Skopje, Macedonia.
Ivan KungulovskiSector of Genetics, Bio Engineering LLC, Skopje, Macedonia.
Zan MitrevLaboratory of Genetics and Personalized Medicine, Zan Mitrev Clinic, Skopje, Macedonia.
Goran KungulovskiSector of Genetics, Bio Engineering LLC, Skopje, Macedonia.
Mitre (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted gene panel testing has the power to interrogate hundreds of genes and evaluate the genetic risk for many types of hereditary cancers simultaneously. We screened a 13-year-old male patient diagnosed with glioblastoma multiforme with the aim to get further insights into the biology of his condition. Herein, we applied gene panel sequencing and identified a heterozygous frameshift mutation c.333_334delTC; p.His112CysfsTer9 in the

Indexed as

case reporthereditary cancer syndromesLi-FraumeniLynch syndromeMLH1next-generation sequencingNorth MacedoniaTP53

Identifiers

PMID31749828
PMCPMC6842924
OpenAlexW2971740204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.