Evidence map›Paper›PMID 31749690›Full record

ArticleFrontiers in human neuroscience2019

Functional and Brain Activation Changes Following Specialized Upper-Limb Exercise in Parkinson's Disease.

Luca Valerio Messa, Federica Ginanneschi, Davide Momi, Lucia Monti, Carla Battisti, David Cioncoloni, Barbara Pucci, Emiliano Santarnecchi, Alessandro Rossi

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Striatal D2-MSN recalibration: A unifying mechanism for exercise-induced recovery in Parkinson's Disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  6. Article
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  11. Review
  12. Review
  13. Article
  14. Changes in corticomotor pathway excitability after exercise training in Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luca Valerio MessaDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Federica GinanneschiDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Davide MomiSiena Brain Investigation and Neuromodulation Lab, Department of Medicine, Surgery and Neurological Sciences, University of Siena, Siena, Italy.
Lucia MontiUnit of Neuroimaging and Neurointervention, Department of Neurological and Neurosensorial Sciences, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Carla BattistiDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
David CioncoloniU.O.P. Professioni della Riabilitazione, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Barbara PucciDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Emiliano SantarnecchiDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Alessandro RossiDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the management of Parkinson's disease (PD), the concept of forced exercise (FE) has drawn interest. In PD subjects, the FE executed with lower limbs has been shown to lessen symptoms and to promote brain adaptive changes. Our study is aimed to investigate the effect of an upper-limb exercise, conceptually comparable with the FE, in PD. Upper-limb exercise was achieved in a sitting position by using a specially designed device (Angel's Wings

Indexed as

ASLEquiTestfMRIforced exerciseParkinson’s diseaseresting-state fMRI

Identifiers

PMID31749690
PMCPMC6843060

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.