Evidence map›Paper›PMID 31749680›Full record

ArticleFrontiers in neuroscience2019

Arousal Contributions to Resting-State fMRI Connectivity and Dynamics.

Yameng Gu, Feng Han, Xiao Liu

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Causal graph neural networks for healthcare.Nature biomedical engineering · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Systemic physiological "noise" in fMRI has clinical relevance.medRxiv : the preprint server for health sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yameng GuDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, United States.
Feng HanDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, United States.
Xiao LiuDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, United States.

Funding

Neural Basis of Resting-State Functional ConnectivityR00NS092996 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI LIU, XIAO · 2017 to 2019
$732k
NINDS NIH HHS R00 NS092996
6 · The paper itself

Abstract

Resting-state functional magnetic resonance imaging (rsfMRI) is being widely used for charting brain connectivity and dynamics in healthy and diseased brains. However, the resting state paradigm allows an unconstrained fluctuation of brain arousal, which may have profound effects on resting-state fMRI signals and associated connectivity/dynamic metrics. Here, we review current understandings of the relationship between resting-state fMRI and brain arousal, in particular the effect of a recently discovered event of arousal modulation on resting-state fMRI. We further discuss potential implications of arousal-related fMRI modulation with a focus on its potential role in mediating spurious correlations between resting-state connectivity/dynamics with physiology and behavior. Multiple hypotheses are formulated based on existing evidence and remain to be tested by future studies.

Indexed as

arousalbrain dynamicsconnectivityglobal signalresting-state fMRI

Identifiers

PMID31749680
PMCPMC6848024

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.