ReviewDialogues in clinical neuroscience2019
Cognition and addiction .
Review in Dialogues in clinical neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Objective and subjective measurement of sleep in people who use substances: Emerging evidence and recommendations from a systematic review.Journal of sleep research · 2025Pooled it
- The repeatable battery for the assessment of neuropsychological status (RBANS) and substance use disorders: a systematic review.Substance abuse treatment, prevention, and policy · 2025Pooled it
- Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study.Addiction (Abingdon, England) · 2023Pooled it
- Effectiveness of the Functional-Cognitive and Sensory Treatment for Improving Daily Functioning of Individuals with Substance Use Disorder: A Randomized Controlled Trial.Substance abuse and rehabilitation · 2026Trial
- Trial
- The Effect of N-Acetylcysteine (NAC) on Neurometabolites and Cognitive Function in Adults With Alcohol Use Disorder: A Preliminary Randomized Controlled Trial.Neuropsychopharmacology reports · 2025Trial
- Cocaine-specific speed-accuracy trade-off during anti-saccade testing differentiates patients with cocaine use disorder who achieve initial abstinence during treatment.Journal of psychopharmacology (Oxford, England) · 2021Trial
- Microglial Activation Is Associated with Hippocampal Synaptic Degeneration and Cognitive Deficits Following Repeated Propofol Exposure.International journal of molecular sciences · 2026Article
- How does cognition change over time in young people who use cannabis recreationally? A narrative review of the longitudinal literature to date.Psychopharmacology · 2026Review
- Opioid use disorder and dementia risk: evidence from observational and genetic analyses in diverse ancestry cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Social cognition in young adults who endorse a cannabis use disorder.Psychopharmacology · 2026Article
- Evidence, Mechanisms and Prospects for Gut Microbiota as a Novel Therapeutic Target for Alcohol Use Disorder.Microbiota and host · 2026Article
- Something is not nothing: Hair-tested substance use and cognitive functions in a large community sample of young adults.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- The informational dysregulation framework of addiction (IDFA): an information-processing model of relapse in opioid use disorder.Frontiers in psychiatry · 2026Article
- Abnormal DLPFC activation in severe methamphetamine use disorder during abstinence: fNIRS evidence from Stroop task.Frontiers in psychiatry · 2026Article
- Anabolic-androgenic steroid use disorder: case for recognition as a substance use disorder with specific diagnostic criteria.The British journal of psychiatry : the journal of mental science · 2026Review
- A computational mechanism linking momentary craving and decision-making in alcohol drinkers and cannabis users.Nature. Mental health · 2026Article
- The Role of Toll-like Receptor 3 Signaling in Cognitive Impairment Induced by Propofol Addiction.Molecular neurobiology · 2025Article
- The (un-)Social Brain in Isolation.Physiological research · 2025Review
- Temporal changes in cognitive functions and associated factors among stimulant users: a 12-month, prospective study.Scientific reports · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this targeted review, we summarize current knowledge on substance-use disorder (SUD)-related cognitive deficits, the link between these deficits and clinical outcomes, and the cognitive training, remediation, and pharmacological approaches that have the potential to rescue cognition. We conclude that: (i) people with SUDs have moderate deficits in memory, attention, executive functions, and decision-making (including reward expectancy, valuation, and learning); (ii) deficits in higher-order executive functions and decision-making are significant predictors of relapse; (iii) cognitive training programs targeting reward-related appetitive biases, cognitive remediation strategies targeting goal-based decision-making, and pharmacotherapies targeting memory, attention, and impulsivity have potential to rescue SUD-related cognitive deficits. We suggest avenues for future research, including developing brief, clinically oriented harmonized cognitive testing suites to improve individualized prediction of treatment outcomes; computational modeling that can achieve deep phenotyping of cognitive subtypes likely to respond to different interventions; and phenotype-targeted cognitive, pharmacological, and combined interventions. We conclude with a tentative model of neuroscience-informed precision medicine. .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.