ArticleNeuropsychiatric disease and treatment2019
Reversion From Mild Cognitive Impairment To Normal Cognition: False-Positive Error Or True Restoration Thanks To Cognitive Control Ability?
Article in Neuropsychiatric disease and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- U shaped association between sleep duration and long term cognitive decline trajectories in a national cohort.Scientific reports · 2025Article
- Characterizing bidirectional transitions in mild cognitive impairment and post-reversion based on longitudinal neuroimaging and cognitive assessments.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Digital Divide and Cognitive Disparities Among Older Adults: Community-Based Cohort Study in China.Journal of medical Internet research · 2024Article
- Development and Validation of Virtual Reality Cognitive Training for Older Adults with Mild Cognitive Impairment: Protocol for a Mixed-Methods Program Evaluation Study.Clinical interventions in aging · 2024Article
- A Pilot Fuzzy System with Virtual Reality for Mild Cognitive Impairment (MCI) Assessment.Healthcare (Basel, Switzerland) · 2023Article
- Mild Cognitive Impairment, Reversion Rates, and Associated Factors: Comparison of Two Diagnostic Approaches.Journal of Alzheimer's disease : JAD · 2023Article
- Association between Changes in Protein Intake and Risk of Cognitive Impairment: A Prospective Cohort Study.Nutrients · 2022Article
- Visuospatial memory impairment as a potential neurocognitive marker to predict tau pathology in Alzheimer's continuum.Alzheimer's research & therapy · 2021Article
- The Subjective Memory Complaints Questionnaire: a systematic review of psychometric properties, clinical applications, and neurobiological correlates.Alzheimer's & dementia (Amsterdam, Netherlands)Review
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeRelatively little attention has been paid to the meaning of reversion from mild cognitive impairment (MCI) to cognitively normal (CN), compared to MCI progression studies. The purpose of the study was to investigate the characteristics contributing to reversion from MCI to CN and to identify the associated factors with such reversion. PATIENTS AND
methodsWe retrospectively identified 200 individuals who initially diagnosed as MCI and completed the second visit from the National Research Center for Dementia (NRCD) registry in Korea. Participants underwent comprehensive clinical and neuropsychological assessments. Factors associated with reversion were examined by a independent-samples t-test, χ
resultsBased on the second assessment, 78 (39%) individuals were found to have reverted to CN (rMCI) and 118 (59%) remained with MCI (sMCI). Four (2%) progressed to Alzheimer's disease dementia and they were excluded from further analysis. Over a wide range of socio-demographic, clinical, and neuropsychological variables, group difference was significant only in neuropsychological tests of cognitive control. Both groups showed improvement in several neuropsychological tests, implying a practice effect, but the rMCI group showed greater improvement.
conclusionReversion from MCI to CN might not be a false-positive error but a true recovery from cognitive impairment. Our results suggest that cognitive control ability may be a characteristic favorable for the restoration of cognitive function. Therefore, assessment of cognitive control might facilitate the development of appropriate interventions for MCI as well as prognosis evaluation.
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