Evidence map›Paper›PMID 31749614›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2019

The Burden Of Chronic Obstructive Pulmonary Disease (COPD) In Finland: Impact Of Disease Severity And Eosinophil Count On Healthcare Resource Utilization.

Arja Viinanen, Mariann I Lassenius, Iiro Toppila, Antti Karlsson, Lauri Veijalainen, Juhana J Idänpään-Heikkilä, Tarja Laitinen

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. The Burden of COPD with Type 2 Inflammation in North-West Continental Europe.International journal of chronic obstructive pulmonary disease · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Relationship of Lymphocyte to High-Density Lipoprotein Ratio with Pulmonary Function in COPD.International journal of chronic obstructive pulmonary disease · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arja Viinanen *Division of Medicine, Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland.ORCID 0000-0003-4990-6228
Mariann I Lassenius *Medaffcon Oy, Espoo, Finland.
Iiro ToppilaMedaffcon Oy, Espoo, Finland.
Antti KarlssonAuria Biobank, Turku University Hospital, Turku, Finland.
Lauri VeijalainenGSK, Espoo, Finland.ORCID 0000-0003-1707-2265
Juhana J Idänpään-HeikkiläGSK, Espoo, Finland.ORCID 0000-0003-3762-5357
Tarja LaitinenDivision of Medicine, Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The burden associated with chronic obstructive pulmonary disease (COPD) is substantial. The objectives of this study were to describe healthcare resource utilization (HCRU) and HCRU-associated costs in patients with COPD in Finland, according to disease severity and blood eosinophil count (BEC). Patients and methods: This non-interventional, retrospective registry study (GSK ID: HO-17-17558) utilized data from the specialist care hospital register. Data extraction was from first hospital visit with a COPD diagnosis (index date) from January 1, 2004 until December 31, 2015 or death. Patients (aged >18 years with ≥1 report of post-bronchodilation forced expiratory volume in 1 s (FEV Results: There were 9042 patients with COPD; 340 non-severe, 326 progressing, 394 severe, and 7982 clinically verified. BEC was available for 31.8% of patients. The mean follow-up time was 3.7-6.5 years in the classified patient-groups. All-cause mortality was 46% during follow-up. Severe COPD was associated with more COPD-related HCRU and higher mortality than non-severe COPD. Patients with BEC ≥300 cells/μL had higher overall HCRU but improved survival compared with those with BEC <300 cells/μL. Overall direct costs were similar across COPD severity categories, 3300-3900€/patient-year, although COPD-related costs were higher in patients with severe versus non-severe COPD. Conclusion: This study demonstrated a substantial burden associated with severe and/or eosinophilic COPD for patients in Finland.

Indexed as

Cost of IllnessEosinophilsHealth Care CostsCause of DeathDisease ProgressionFinlandForced Expiratory VolumeHealth ResourcesHumansLeukocyte CountLungPrevalencePulmonary Disease, Chronic ObstructiveRegistriesRetrospective StudiesSeverity of Illness Indexhealthcare costsmortalityprevalencesevere COPDsevere eosinophilic COPD

Identifiers

PMID31749614
PMCPMC6818542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.