Evidence map›Paper›PMID 31749578›Full record

ArticleVeterinary world2019

Anticancer activities of toxic isolate of

Made Dira Swantara, Wiwik Susanah Rita, Nyoman Suartha, Kadek Karang Agustina

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Analysis of Marrubiin inMetabolites · 2023
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  5. Article
  6. Review
  7. Article
  8. Neuroprotective Effect of Red Sea Marine SpongePharmaceuticals (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Cervical anticancer activities ofVeterinary world · 2022
    Article
  11. Structure-Activity Relationship of Cytotoxic Natural Products from Indonesian Marine Sponges.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2022
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Made Dira SwantaraDepartment of Applied Chemistry, Graduate School, Udayana University, Denpasar, Indonesia.
Wiwik Susanah RitaDepartment of Chemistry, Udayana University, Badung, Indonesia.
Nyoman SuarthaDepartment of Internal Medicine, Faculty of Veterinary Medicine, Udayana University, Denpasar, Indonesia.
Kadek Karang AgustinaDepartment of Public Health, Faculty of Veterinary Medicine, Udayana University, Denpasar, Indonesia.
Udayana University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe purposes of this study were to determine the anticancer activity of MATERIALS AND

methodsThe metabolites were extracted using methanol maceration at room temperature. The separation and purification of metabolites were performed using fractionation and column chromatography. The toxicity was examined using the brine shrimp lethality assay, and the toxic isolates were tested for anticancer activity against HeLa cells. Gas chromatography-mass spectrometry analysis was used to identify the compounds in the isolate.

resultsWhen the methanol extract was partitioned with n-hexane, chloroform, and n-butanol, the chloroform fraction was the most toxic, with a concentration that results in 50% lethality (LC

conclusionThese findings indicate that the isolate of

Indexed as

anticancer activityHeLa cellXestospongia testudinaria

Identifiers

PMID31749578
PMCPMC6813599
OpenAlexW2974149730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.