Evidence map›Paper›PMID 31749576›Full record

ArticleVeterinary world2019

Comparative immune responses of pups following modified live virus vaccinations against canine parvovirus.

Jayalakshmi Vasu, Mouttou Vivek Srinivas, Prabhakar Xavier Antony, Jacob Thanislass, Vijayalakshmi Padmanaban, Hirak Kumar Mukhopadhyay

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Impact of VP2 mutations on viral fitness in canine parvovirus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jayalakshmi VasuDepartment of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
Mouttou Vivek SrinivasDepartment of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
Prabhakar Xavier AntonyDepartment of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
Jacob ThanislassDepartment of Veterinary Biochemistry, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
Vijayalakshmi PadmanabanDepartment of Veterinary Medicine, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
Hirak Kumar MukhopadhyayDepartment of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
Rajiv Gandhi University of Health Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimCanine parvovirus (CPV) is the most important viral cause of enteritis and mortality in pups. Evaluation and monitoring of pre- and post-vaccine immune responses may help to determine the efficacy of the current vaccination schedule being followed in pups in India. This study aimed to evaluate and monitor the pre- and post-vaccine immune responses of CPV vaccinated pups using hemagglutination inhibition (HI) assay. The neutralizing antibody titer levels were also detected using serum neutralization test (SNT). MATERIALS AND

methodsThe pups were categorized into two groups, the double booster and the single booster groups. In this study, serum samples were subjected to HI and SNT for measuring the CPV antibody titer at frequent intervals for up to 6 months from 27 healthy pups following primary and booster CPV vaccinations.

resultsThe antibody titers in double booster pups reached their peaks at the 21

conclusionThe double booster pups maintained a higher immune response throughout the period of the study compared to single booster pups though the difference in titers was not statistically significant. SNT results indicated that the raised antibody titer was also able to yield virus-neutralizing antibodies. No interfering maternally derived antibodies were found in the pups at the age of primary vaccination (45

Indexed as

canine parvovirushemagglutination inhibition testserum neutralization testvaccine immune responses

Identifiers

PMID31749576
PMCPMC6813607
OpenAlexW2973975255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.