Evidence map›Paper›PMID 31749120›Full record

ArticleMolecular biology reports2020

Inhibitory mechanism of Penicillin V on mushroom tyrosinase.

Xin Dong, Shaoyu Wang, Lian Xu, Juan Lin, Xinqi Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xin DongTuolong Biotechnological Developmental Ltd Co., Guangzhou, 510800, China.
Shaoyu WangCollege of Biological Science and Engineering, Fuzhou University, Fuzhou, 350116, China.
Lian XuCollege of Biological Science and Engineering, Fuzhou University, Fuzhou, 350116, China.
Juan LinCollege of Biological Science and Engineering, Fuzhou University, Fuzhou, 350116, China. ljuan@fzu.edu.cn.
Xinqi XuCollege of Biological Science and Engineering, Fuzhou University, Fuzhou, 350116, China. xuxinqi@fzu.edu.cn.
Fuzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penicillin V is a bacteriolytic β-lactam antibiotic drug. In the present work, we investigated the inhibitory effect of Penicillin V on the activity of mushroom tyrosinase for the first time. The molecular mechanism for the inhibition of tyrosinase by Penicillin V was investigated by means of kinetics analysis, fluorescence quenching and molecular docking techniques. The results showed that Penicillin V could inhibit both monophenolase and diphenolase activities with IC

Indexed as

AgaricalesAnti-Bacterial AgentsCatalysisCatalytic DomainEnzyme InhibitorsInhibitory Concentration 50KineticsMolecular Docking SimulationMonophenol MonooxygenasePenicillin VAnti-Bacterial AgentsEnzyme InhibitorsMonophenol MonooxygenasePenicillin VFluorescence quenchingInhibition mechanismMolecular dockingPenicillin VTyrosinase

Identifiers

PMID31749120
OpenAlexW2989700990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.