Evidence map›Paper›PMID 31749037›Full record

ArticleEcotoxicology (London, England)2020

Esterase-mediated spinosad resistance in house flies Musca domestica (Diptera: Muscidae).

Yi Zhang, Mingcheng Guo, Zhuo Ma, Chunmei You, Xiwu Gao, Xueyan Shi

Abstract read
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In one paragraph

Article in Ecotoxicology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yi ZhangState Key Lab Breeding Base for Zhejiang Sustainable Plant Pest Control, MOA Key Lab for Pesticide Residue Detection, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
Mingcheng GuoInstitute for the Control of Agrochemicals, Ministry of Agriculture and Rural Affairs, Beijing, 100125, China.
Zhuo MaDepartment of Entomology, China Agricultural University, Beijing, 100193, China.
Chunmei YouDepartment of Entomology, China Agricultural University, Beijing, 100193, China.
Xiwu GaoDepartment of Entomology, China Agricultural University, Beijing, 100193, China. gaoxiwu@263.net.cn.
Xueyan ShiDepartment of Entomology, China Agricultural University, Beijing, 100193, China. shixueyan@cau.edu.cn.
China Agricultural University · CNMinistry of Agriculture and Rural Affairs · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although esterase-mediated spinosad resistance has been proposed for several insects, the associated molecular mechanism remains poorly understood. In this study, we investigated the mechanism of esterase-based spinosad resistance in house flies using a susceptible strain (SSS) and a spinosad-resistant, near-isogenic line (N-SRS). Combined with the synergistic effect of DEF on spinosad in the N-SRS strain, decreased ali-esterase activity in the spinosad-resistant strain has implicated the involvement of mutant esterase in spinosad resistance in house flies. Examination of the carboxylesterase gene MdαE7 in the two strains revealed that four non-synonymous mutations (Trp

Indexed as

AnimalsCarboxylesteraseDrug CombinationsFemaleHousefliesInsecticide ResistanceInsecticidesMacrolidesCarboxylesteraseDrug CombinationsInsecticidesMacrolidesspinosadCaboxylesteraseMdαE7Musca domesticaSpinosad resistance

Identifiers

PMID31749037
OpenAlexW2989582068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.