ArticleEnvironmental science and pollution research international2020
Reference values for trace essential elements in the whole blood and serum samples of the adult Serbian population: significance of selenium deficiency.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Exploring the Impact of Selenium Supplementation on Nutritional, Inflammatory, and Cardiac Function in Chronic Heart Failure Patients: A Novel Approach to Managing Deficiency.Cardiovascular toxicology · 2025Pooled it
- Environmental and Population Biomonitoring of Selenium in Eastern Croatia.Journal of xenobiotics · 2026Article
- Trace Mineral Imbalances in Global Health: Challenges, Biomarkers, and the Role of Serum Analysis.Nutrients · 2025Review
- Selenium Nutritional Status Assessment in Chinese Adult Females: Results from the China Nutrition and Health Surveillance in 2015.Nutrients · 2025Article
- Serum and Seminal Plasma Zinc Levels and Immunopositivity of the ZIP6 and ZIP14 Transporters in Men with Normo- and Teratozoospermia.Current issues in molecular biology · 2025Article
- Impact of selenium and selenoproteins on idiopathic male infertility: a comprehensive review.Frontiers in nutrition · 2025Review
- Association Between Essential Trace Elements and Thyroid Antibodies in the Blood of Women with Newly Diagnosed Hashimoto's Thyroiditis.International journal of endocrinology and metabolism · 2024Article
- Selenium Status: Its Interactions with Dietary Mercury Exposure and Implications in Human Health.Nutrients · 2022Review
- Elemental Composition of Pheochromocytoma Resolved on Solid/Adrenal Tissue and Whole Blood Level.Biological trace element research · 2022Article
- Circulatory Imbalance of Essential and Toxic Trace Elements in Pre-dialysis and Hemodialysis Patients.Biological trace element research · 2022Article
- Reference Ranges of Selenium in Plasma and Whole Blood for Child-Bearing-Aged Women in China.International journal of environmental research and public health · 2022Article
- Serum selenium levels and asthma among seafood processing workers in Greenland.International journal of circumpolar health · 2021Article
- Environmental metal toxicity assessment by the combined application of metallomics and metabolomics.Environmental science and pollution research international · 2021Review
- Trace Element Analysis in Whole Blood and Plasma for Reference Levels in a Selected Queensland Population, Australia.International journal of environmental research and public health · 2021Article
- Zinc Deficiency, Plasma Fatty Acid Profile and Desaturase Activities in Hemodialysis Patients: Is Supplementation Necessary?Frontiers in nutrition · 2021Article
- The Correlation Between Whole Blood Copper (Cu), Zinc (Zn) Levels and Cu/Zn Ratio and Sepsis-Induced Left Ventricular Systolic Dysfunction (SILVSD) in Patients with Septic Shock: A Single-Center Prospective Observational Study.International journal of general medicine · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was aimed to determine reference values (RVs) for the manganese (Mn), copper (Cu), zinc (Zn), and selenium (Se) in the whole blood (B) and serum (S) samples of the Serbian population. Blood specimens were collected from healthy persons (n = 295; women/men ratio = 149/146; mean age: 42 ± 2 years). The RVs were calculated as lower limit (LL) and upper limit (UL) of the 95% confidence interval (CI) and were expressed as percentiles (P) in the range from P2.5 to P97.5. The influences of sex, age, and smoking habits on element profiles were considered. It was found that the contents of B-Cu and S-Cu were higher in women, while the contents of B-Zn and S-Zn were higher in men. Both trace elements were significantly increased in a group of persons above 40 when compared to a younger persons (≤ 40 years). According to smoking habits, increased content was found only for S-Mn in the nonsmoker's group (p < 0.05). Comparing our results to the results reported in other population groups worldwide, the Serbian population had significantly reduced content of Se in both types of samples. This finding could highlight the deficiency of Se in the investigated Serbian population and could contribute to the better understanding of the molecular basis for the increased incidence of thyroid and other diseases in which selenium plays a key role.
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