Evidence map›Paper›PMID 31748845›Full record

ArticleMikrochimica acta2019

A redox modulated ratiometric fluorometric method based on the use of dual-color carbon dots for determination of the activity of enzymes participating in ascorbic acid-related reactions.

Xia Cheng, Jian Xu, Lin Wang, Guanhong Xu, Fangdi Wei, Yuying Chai, Qin Hu, Yao Cen

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xia ChengSchool of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China.
Jian XuDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China.
Lin WangDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China.
Guanhong XuSchool of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China.
Fangdi WeiSchool of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China.
Yuying ChaiSchool of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China.
Qin HuSchool of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China. huqin@njmu.edu.cn.ORCID 0000-0002-4077-8760
Yao CenSchool of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, People's Republic of China. yaocen@njmu.edu.cn.
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

National Natural Science Foundation of China No. 61775099, 21705080Natural Science Foundation of Jiangsu Province No. BK20171487, BK20171043R&D fund for Smart Health Technology Innovation of Nanjing Medical University and Jiangsu Salt Group No. NMU-SY201801Science and Technology Development Fund of Nanjing Medical University-Major Project No.NMUD2018004
6 · The paper itself

Abstract

A turn-on ratiometric fluorescent assay is described for the determination of the activity of enzymes participating in ascorbic acid-forming reactions. Blue-emitting carbon dots (bCDs; with excitation/emission wavelength at 380/450 nm) serve as fluorescent indicator. Their fluorescence is reduced by Fe

Indexed as

ColorFluorometryAlkaline Phosphatasealpha-GlucosidasesAscorbic AcidCarbonHumansOxidation-ReductionParticle SizeQuantum DotsSurface PropertiesAlkaline Phosphatasealpha-GlucosidasesAscorbic AcidCarbonAlkaline phosphataseAscorbic acid-relatedDual-color carbon dotsHuman serumInhibitors screeningInner filter effectRatiometric fluorometryα-Glucosidase

Identifiers

PMID31748845
OpenAlexW2989793821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.