ArticleScientific reports2019
Negative frequency dependent selection on plasmid carriage and low fitness costs maintain extended spectrum β-lactamases in Escherichia coli.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 39 citations in OpenAlex.
- Exploring cooperation among social pathogens: a computational perspective.FEMS microbiology reviews · 2026Review
- Cooperative antibiotic resistance in bacteria: beyond biofilms.Frontiers in microbiology · 2026Review
- Local negative frequency dependence can decrease global coexistence in fragmented populations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Plasmid-driven strategies for clone success in Escherichia coli.Nature communications · 2025Article
- The metabolic burden associated with plasmid acquisition: An assessment of the unrecognized benefits to host cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- When does antimicrobial resistance increase bacterial fitness? Effects of dosing, social interactions, and frequency dependence on the benefits of AmpCEvolution letters · 2024Article
- Frequency-dependent ecological interactions increase the prevalence, and shape the distribution, of pre-existing drug resistance.bioRxiv : the preprint server for biology · 2024Article
- Decolonizing drug-resistantMicrobiology (Reading, England) · 2023Article
- Genomics and pathotypes of the many faces of Escherichia coli.FEMS microbiology reviews · 2022Article
- Potential Synergistic Antibiotic Combinations against Fluoroquinolone-ResistantPharmaceuticals (Basel, Switzerland) · 2022Article
- Risk factors for third-generation cephalosporin-resistant and extended-spectrum β-lactamase-producing Escherichia coli carriage in domestic animals of semirural parishes east of Quito, Ecuador.PLOS global public health · 2022Article
- Large-Scale Analysis of Fitness Cost ofFrontiers in cellular and infection microbiology · 2022Article
- Evolutionary Pathways and Trajectories in Antibiotic Resistance.Clinical microbiology reviews · 2021Article
- Article
- Increased copy number couples the evolution of plasmid horizontal transmission and plasmid-encoded antibiotic resistance.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Conjugation dynamics depend on both the plasmid acquisition cost and the fitness cost.Molecular systems biology · 2021Article
- Role of Plasmids in the Ecology and Evolution of "High-Risk" Extraintestinal PathogenicEcoSal Plus · 2021Review
- Plasmids shape the diverse accessory resistomes ofAccess microbiology · 2021Article
- Strong Environment-Genotype Interactions Determine the Fitness Costs of Antibiotic ResistanceAntimicrobial agents and chemotherapy · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Plasmids may maintain antibiotic resistance genes in bacterial populations through conjugation, in the absence of direct selection pressure. However, the costs and benefits of conjugation for plasmid and bacterial fitness are not well understood. Using invasion and competition experiments with plasmid mutants we explicitly tested how conjugation contributes to the maintenance of a plasmid bearing a single extended-spectrum ß-lactamase (ESBL) gene (bla
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.