ArticleJournal of virology2020
Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family.
Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Structures of African swine fever virus topoisomerase complex and their implications.Nature communications · 2024Article
- Recent progress on gene-deleted live-attenuated African swine fever virus vaccines.NPJ vaccines · 2024Review
- African swine fever virus MGF360-4L protein attenuates type I interferon response by suppressing the phosphorylation of IRF3.Frontiers in immunology · 2024Article
- Identification of two novel linear epitopes on the E165R protein of African swine fever virus recognized by monoclonal antibodies.Frontiers in veterinary science · 2024Article
- Complete Structural Predictions of the Proteome of African Swine Fever Virus Strain Georgia 2007.Microbiology resource announcements · 2022Article
- Structural Insight into Molecular Inhibitory Mechanism of InsPJournal of virology · 2022Article
- Deletion of theJournal of virology · 2022Article
- Viral dUTPases: Modulators of Innate Immunity.Biomolecules · 2022Review
- Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies.Viruses · 2021Article
- African Swine Fever Virus E120R Protein Inhibits Interferon Beta Production by Interacting with IRF3 To Block Its Activation.Journal of virology · 2021Article
- Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development.The Journal of biological chemistryArticle
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The African swine fever virus (ASFV) is the deadly pathogen of African swine fever (ASF) that induces high mortality, approaching 100% in domestic pigs, causes enormous losses to the global pig industry, and threatens food security. Currently, there is no effective treatment or preventive countermeasure. dUTPases (deoxyuridine 5'-triphosphate pyrophosphatases) are ubiquitous enzymes that are essential for the hydrolysis of dUTP and prevent the misincorporation of dUTP into newly synthesized DNA. Here, we present the crystal structures of the ASFV dUTPase in complex with the product dUMP and cofactor Mg
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.