Evidence map›Paper›PMID 31748322›Full record

ArticleJournal of clinical microbiology2020

Clinical Validation of the Aptima Bacterial Vaginosis and Aptima

Jane R Schwebke, Stephanie N Taylor, Ronald Ackerman, Robert Schlaberg, Neil B Quigley, Charlotte A Gaydos, Steven E Chavoustie, Paul Nyirjesy, Carmelle V Remillard, Philip Estes and 3 more

Open access · hybridAbstract readClinical StudyComparative StudyMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Non-Frontiers in microbiology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Women presenting to emergency departments with vaginitis should be offered single-dose empirical treatment.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
  11. Bacterial vaginosis.Nature reviews. Disease primers · 2025
    Review
  12. Article
  13. Article
  14. Rapid Molecular Diagnostics in Vulvovaginal Candidosis.Diagnostics (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. State of the Art for Diagnosis of Bacterial Vaginosis.Journal of clinical microbiology · 2023
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Jane R SchwebkeUniversity of Alabama at Birmingham, Birmingham, Alabama, USA jschwebk@uabmc.edu.
Stephanie N TaylorLouisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Ronald AckermanComprehensive Clinical Trials, West Palm Beach, Florida, USA.
Robert SchlabergUniversity of Utah, Salt Lake City, Utah, USA.
Neil B QuigleyGeneuity CRS, Maryville, Tennessee, USA.
Charlotte A GaydosJohns Hopkins University, Baltimore, Maryland, USA.
Steven E ChavoustieSegal Trials, Miami, Florida, USA.
Paul NyirjesyDrexel University, Philadelphia, Pennsylvania, USA.
Carmelle V RemillardHologic, Inc., San Diego, California, USA.
Philip EstesHologic, Inc., San Diego, California, USA.
Byron McKinneyHologic, Inc., San Diego, California, USA.
Damon K GetmanHologic, Inc., San Diego, California, USA.
Craig ClarkHologic, Inc., San Diego, California, USA.
Hologic (United States) · USComprehensive Clinical Trials · USDrexel University · USJohns Hopkins University · USLouisiana State University Health Sciences Center New Orleans · USSegal Institute for Clinical Research · USUniversity of Alabama at Birmingham · USUniversity of Utah · US

Funding

LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Susan Anne Tuddenham · 2007 to 2026
$34.6M
NIAID NIH HHS UM1 AI068613NIBIB NIH HHS U54 EB007958
6 · The paper itself

Abstract

Infectious vaginitis due to bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and

Indexed as

AdolescentAdultAgedBacteriaCandidaCandidiasis, VulvovaginalCross-Sectional StudiesFemaleHumansMiddle AgedNucleic Acid Amplification TechniquesProspective StudiesReagent Kits, DiagnosticSensitivity and SpecificityTrichomonas vaginalisTrichomonas VaginitisReagent Kits, DiagnosticAmsel criteriaAptimabacterial vaginosiscandidiasisclinician’s diagnosisdiagnostic accuracymolecular testNugent scoresensitivityspecificitytrichomoniasis

Identifiers

PMID31748322
PMCPMC6989072
OpenAlexW2990575861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.