Evidence map›Paper›PMID 31748253›Full record

Trial reportPediatrics2019

Prenatal and Infancy Nurse Home Visiting Effects on Mothers: 18-Year Follow-up of a Randomized Trial.

David L Olds, Harriet Kitzman, Elizabeth Anson, Joyce A Smith, Michael D Knudtson, Ted Miller, Robert Cole, Christian Hopfer, Gabriella Conti

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06160037 (Influence of Prenatal and Early Childhood Home-Visiting by Nurses on Development of Chronic Disease), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06160037 nacompletednot on this mapstarted 2020, after this paper: background citation

Influence of Prenatal and Early Childhood Home-Visiting by Nurses on Development of Chronic Disease: 29-year Follow-Up of a Randomized Clinical Trial

TypeinterventionalSponsorUniversity of Colorado, DenverRan2020 to 2024Enrolled1,055ConditionsChronic DiseaseArmsTransportation and Developmental Screening, Transportation, Screening, and Nurse-Visitation during Pregnancy and Infancy
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. A Mental Health Innovation for Nurse Home Visiting Program Shows Effectiveness in Reducing Depressive Symptoms and Anxiety.Prevention science : the official journal of the Society for Prevention Research · 2024
    Trial
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  11. Home visiting for postpartum depression.The Cochrane database of systematic reviews · 2025
    Article
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  14. Article
  15. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

David L OldsDepartments of Pediatrics and david.olds@cuanschutz.edu.
Harriet KitzmanSchool of Nursing, University of Rochester, Rochester, New York.
Elizabeth AnsonSchool of Nursing, University of Rochester, Rochester, New York.
Joyce A SmithSchool of Nursing, University of Rochester, Rochester, New York.
Michael D KnudtsonDepartments of Pediatrics and.
Ted MillerPacific Institute for Research and Evaluation, School of Public Health, Curtin University, Perth, Australia; and.
Robert ColeSchool of Nursing, University of Rochester, Rochester, New York.
Christian HopferPsychiatry, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Gabriella ContiDepartments of Economics and Social Science, University College London, London, United Kingdom.

Funding

Age-17 Follow-up of Home Visiting InterventionR01DA021624 · NIDA · UNIVERSITY OF ROCHESTER · PI OLDS, DAVID L · 2008 to 2012
$8.4M
NIDA NIH HHS R01 DA021624
6 · The paper itself

Abstract

backgroundPrenatal and infancy home-visiting by nurses is promoted as a means of improving maternal life-course, but evidence of long-term effects is limited. We hypothesized that nurse-visitation would lead to long-term reductions in public-benefit costs, maternal substance abuse and depression, and that cost-savings would be greater for mothers with initially higher psychological resources.

methodsWe conducted an 18-year follow-up of 618 out of 742 low-income, primarily African-American mothers with no previous live births enrolled in an randomized clinical trial of prenatal and infancy home visiting by nurses. We compared nurse-visited and control-group women for public-benefit costs, rates of substance abuse and depression, and examined possible mediators of intervention effects.

resultsNurse-visited women, compared with controls, incurred $17 310 less in public benefit costs (

conclusionsThrough child age 18, the program reduced public-benefit costs, an effect more pronounced for mothers with higher psychological resources and mediated by subsequent pregnancy planning. There were no effects on maternal substance abuse and depression.

Indexed as

MothersAdultFemaleFollow-Up StudiesHome Care ServicesHouse CallsHumansInfantInfant, NewbornMaleMaternal HealthNurses, Community HealthPovertyPregnancyPrenatal CareTime Factors

Identifiers

PMID31748253
PMCPMC6889935

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.