Evidence map›Paper›PMID 31748248›Full record

ArticlemSphere2019

Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans.

Yee-Seul So, Shinae Maeng, Dong-Hoon Yang, Hyelim Kim, Kyung-Tae Lee, Seong-Ryong Yu, Jennifer L Tenor, Vinay K Giri, Dena L Toffaletti, Samantha Arras and 3 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A Quick reCAP: DiscoveringJournal of fungi (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Oxidative stress response pathways in fungi.Cellular and molecular life sciences : CMLS · 2022
    Review
  9. A case of HIV negative cryptococcal meningitis with antiphospholipid syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Yee-Seul So *Department of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Shinae Maeng *Department of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Dong-Hoon YangDepartment of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Hyelim KimDepartment of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Kyung-Tae LeeDepartment of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Seong-Ryong YuDepartment of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Jennifer L TenorDepartment of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Vinay K GiriDepartment of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Dena L ToffalettiDepartment of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Samantha ArrasAustralian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.
James A FraserAustralian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.
John R PerfectDepartment of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Yong-Sun BahnDepartment of Biotechnology, Center for Fungal Pathogenesis, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea ysbahn@yonsei.ac.kr.
Yonsei University · KRDuke University · USUniversity of Queensland · AU

Funding

Pathobiology of C. neoformans in the Central Nervous SystemR01AI073896 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2008 to 2018
$4.4M
Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDSR01AI093257 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2011 to 2022
$3.8M
NIAID NIH HHS R01 AI073896NIAID NIH HHS R01 AI093257
6 · The paper itself

Abstract

AP-1-like transcription factors play evolutionarily conserved roles as redox sensors in eukaryotic oxidative stress responses. In this study, we aimed to elucidate the regulatory mechanism of an atypical yeast AP-1-like protein, Yap1, in the stress response and virulence of

Indexed as

Gene Expression Regulation, FungalStress, PhysiologicalAnimalsCryptococcosisCryptococcus neoformansDisease Models, AnimalDNA Mutational AnalysisFungal ProteinsGene Expression ProfilingMice, Inbred BALB CMicrobial ViabilityOxidative StressProtein TransportSequence DeletionTranscription FactorsVirulenceFungal ProteinsTranscription FactorsAP-1-like transcription factorC. neoformansMpk1Yap1

Identifiers

PMID31748248
PMCPMC6887862
OpenAlexW2991068400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.