Evidence map›Paper›PMID 31748204›Full record

ArticleDevelopment (Cambridge, England)2019

Dynamics of activating and repressive histone modifications in

Merve Deniz Abdusselamoglu, Lisa Landskron, Sarah K Bowman, Elif Eroglu, Thomas Burkard, Robert E Kingston, Jürgen A Knoblich

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Epigenetic Regulation in Drosophila Tumor Models.Advances in experimental medicine and biology · 2025
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Merve Deniz AbdusselamogluInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.ORCID 0000-0001-8467-3947
Lisa LandskronInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.ORCID 0000-0003-0405-2046
Sarah K BowmanDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Elif ErogluInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.
Thomas BurkardInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.
Robert E KingstonDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
Jürgen A KnoblichInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria juergen.knoblich@imba.oeaw.ac.at.ORCID 0000-0002-6751-3404
Institute of Molecular Biotechnology · ATHarvard University · US

Funding

Functional Analysis of Epigenetic ComplexesR35GM131743 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI ROBERT KINGSTON · 2019 to 2026
$7.0M
TRANSCRIPTION FACTOR INTERACTIONS WITH NUCLEOSOMESR01GM048405 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI KINGSTON, ROBERT · 1993 to 2008
$3.1M
Austrian Science Fund FWF Z 153European Research Council 250342NIGMS NIH HHS R01 GM048405NIGMS NIH HHS R35 GM131743
6 · The paper itself

Abstract

During central nervous system development, spatiotemporal gene expression programs mediate specific lineage decisions to generate neuronal and glial cell types from neural stem cells (NSCs). However, little is known about the epigenetic landscape underlying these highly complex developmental events. Here, we perform ChIP-seq on distinct subtypes of

Indexed as

Protein Processing, Post-TranslationalAnimalsBrain NeoplasmsDrosophila melanogasterDrosophila ProteinsHistonesNeoplasm ProteinsNeoplastic Stem CellsNeural Stem CellsDrosophila ProteinsHistonesNeoplasm ProteinsDrosophilaHistone modificationsNeurogenesisPolycombTrithorax

Identifiers

PMID31748204
PMCPMC7055365
OpenAlexW2990456625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.