Evidence map›Paper›PMID 31747662›Full record

Observational studyObesity facts2019

Long-Term Weight Loss and Metabolic Syndrome Remission after Bariatric Surgery: The Effect of Sex, Age, Metabolic Parameters and Surgical Technique - A 4-Year Follow-Up Study.

Vanessa Guerreiro, João Sérgio Neves, Daniela Salazar, Maria João Ferreira, Sofia Castro Oliveira, Pedro Souteiro, Jorge Pedro, Daniela Magalhães, Ana Varela, Sandra Belo and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Obesity facts, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
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  4. Article
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  11. Determinants of Weight Loss and Regain in Men After Roux-En-Y Gastric Bypass: A Retrospective Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
  12. Article
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  16. Article
  17. Bariatric surgery: time to study sex.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2023
    Article
  18. Diabetic Markers, Five Years after Bariatric Surgery.Middle East journal of digestive diseases · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Vanessa GuerreiroDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal, vanessa.a.guerreiro@gmail.com.
João Sérgio NevesDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Daniela SalazarDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Maria João FerreiraDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Sofia Castro OliveiraDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Pedro SouteiroDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Jorge PedroDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Daniela MagalhãesDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Ana VarelaDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Sandra BeloDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Paula FreitasDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Davide CarvalhoDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
AMTCO Group
Universidade do Porto · PTHospital de São João · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBariatric surgery is an effective treatment for morbid obesity and its metabolic related comorbidities. However, the literature reports inconsistent results regarding weight loss (WL) and the resolution of comorbidities associated with obesity.

objectiveWe aim to evaluate long-term differences in WL between different surgical techniques and the impact of each surgical technique on metabolic parameters (type 2 diabetes mellitus [T2DM], dyslipidemia,hypertension, and metabolic syndrome). We also aim to evaluate the effect of baseline clinical characteristics in WL and in the evolution of metabolic syndrome (MetS) components. Our hypothesis is that different types of surgery have different effects on WL and the prevalence of comorbidities over time.

methodsWe retrospectively evaluated WL and metabolic parameter remission (T2DM, dyslipidemia, hypertension, and MetS) during 4 years in 1,837 morbidly obese patients (females, 85%; age, 42.5 ± 10.6 years; BMI, 44.0 ± 5.8) who underwent bariatric surgery (Roux-en-Y gastric bypass [RYGB], laparoscopic sleeve gastrectomy [LSG], and laparoscopic adjustable gastric band [LAGB]).

resultsThe mean percentage of WL for RYGB, LSG, and LAGB was, respectively, 32.9 ± 8.7, 29.8 ± 9.8, and 16.2 ± 9.6 at 12 months and 30.6 ± 9.1, 22.7 ± 10.0, and 15.8 ± 10.8 at 48 months (p < 0.001), even after adjustment for baseline weight, BMI, age, and sex (p < 0.001). Women had more WL during the first 36 months (p = 0.013 and 0.007 at 12 and 36 months, respectively) and older patients had less WL compared to younger ones (p <0.001), except at 48 months. Patients with T2DM had less WL than those without diabetes after adjustment (sex, age, and surgical technique) during the same period. Patients with hypertension had less WL at 12 months (p = 0.009) and MetS at 24 months (p = 0.020) compared to those without these comorbidities. There was no significant difference regarding the presence of dyslipidemia in WL. The RYGB group showed better results for MetS resolution.

conclusionDuring the 4-year follow-up, RYGB was the surgical procedure that caused the highest WL and MetS resolution.

Indexed as

Bariatric SurgeryAdultAge FactorsComorbidityDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGastrectomyGastric BypassHumansLaparoscopyMaleMetabolic SyndromeMiddle AgedObesity, MorbidRemission InductionBariatric surgeryMetabolic syndromeMorbid obesityWeight loss

Identifiers

PMID31747662
PMCPMC6940448
OpenAlexW2990772507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.