ReviewJornal de pediatria
The challenges of neonatal sepsis management.
Review in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 181 citations in OpenAlex.
- The burden of neonatal sepsis and its risk factors in Africa. a systematic review and meta-analysis.BMC public health · 2025Pooled it
- A meta-analysis of the association between inflammatory cytokine polymorphism and neonatal sepsis.PloS one · 2024Pooled it
- The role of STORCH infections in shaping neurodevelopment: a longitudinal case-control study in preterm children.BMC pediatrics · 2026Article
- Sulodexide protects against sepsis-induced liver injury in neonatal rat by attenuating oxidative stress, apoptosis, and NF-κB/MAPK signaling.Molecular biology reports · 2026Article
- [Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Assessment of Serum Interleukins 18 and 22 in Predicting Neonatal Sepsis and Mortality: A Case-Control Study.Clinical medicine insights. Pediatrics · 2026Article
- Upregulation of miR-223 by SIRT1 attenuates the inflammatory response in neonatal sepsis.BMC immunology · 2026Article
- Application of Umbilical Cord Blood for the Clinical Prevention and Treatment of Complications in Preterm Infants(Review).Stem cell reviews and reports · 2026Review
- Bacterial prevalence and inflammatory changes in positive blood culture in community-acquired neonatal sepsis in Jordan.IJID regions · 2025Article
- Assessment of the diagnostic significance of pentraxin-3 in conjunction with procalcitonin (PCT) and C-reactive protein (CRP) for neonatal sepsis.BMC infectious diseases · 2025Article
- Establishment of a neonatal nursery in a rural district hospital in Malawi: a retrospective review of neonatal outcomes in Neno District Hospital (2014-2021).BMC pediatrics · 2025Article
- Comparative analysis of inflammatory biomarkers for the diagnosis of neonatal sepsis: IL-6, IL-8, SAA, CRP, and PCT.Open life sciences · 2025Article
- Article
- Lipopolysaccharide induced systemic inflammation and heart rate variability in a term newborn piglet model.Pediatric research · 2025Article
- Identification of risk factors for necrotizing enterocolitis in twins: a case-control matching analysis of over ten-years' experience.BMC pediatrics · 2024Article
- Maternal factors associated with early-onset neonatal sepsis among caesarean-delivered babies at Mbarara Regional Referral Hospital, Uganda: a case-control study.BMC pregnancy and childbirth · 2024Article
- [Recommendations for antibiotic use in hospitalized preterm infants with late-onset sepsis in the neonatal intensive care unit].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Mean platelet volume in preterm infants as a predictor of late-onset neonatal sepsis: a retrospective comparative study.BMJ paediatrics open · 2024Article
- Hyperbilirubinemia and retinopathy of prematurity: a retrospective cohort study.European journal of pediatrics · 2024Observational
- Factors associated with neonatal sepsis among neonates admitted in Kibungo Referral Hospital, Rwanda.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo present current evidence on the etiology, risk factors, diagnosis, and management of early and late neonatal sepsis. SOURCE OF DATA: Non-systematic review of the Medline (PubMed), Scopus, Web of Science, Cochrane, and Google Scholar databases regarding the following terms: neonatal sepsis, early neonatal sepsis, late neonatal sepsis, empirical antibiotic therapy, sepsis calculator, vancomycin, newborn, preterm newborn. DATA SYNTHESIS: Neonatal sepsis is a frequent cause of neonatal morbidity and mortality. Its diagnosis is difficult. Continuous observation of the patient is critical to diagnostic suspicion. When neonatal sepsis is suspected, bacteriological tests should be collected. Vancomycin should not be routinely using in the empirical antibiotic regimen in late neonatal sepsis, and the main protective mechanisms against neonatal sepsis are handwashing and the use of breast milk.
conclusionsNewborns constitute a group that is more vulnerable to sepsis. Knowledge of risk factors and etiological agents allows a better approach to the newborn with sepsis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.